This $248,865 Cooperative Agreement was awarded by the Department of Commerce National Institute of Standards and Technology (NIST) under the Measurement and Engineering Research and Standards program (CFDA 11.609). The purpose of this two-year project is to develop large public datasets from new sequencing technologies for public genomes from the Genome in a Bottle Consortium and NIST reference materials. The recipient, Northeastern University, will generate high-quality nanopore sequencing...
The National Human Genome Research Institute (NHGRI), under the Federal Grant Program "Human Genome Research" (CFDA 93.172), awarded a $407,291 Phase I Small Business Innovation Research (SBIR) grant to Electronic Biosciences, Inc. to develop a nanopore-based protein sequencing platform. The project aims to create a high-accuracy, label-free nanopore reader capable of direct, single-molecule protein sequencing. This novel technology would enable proteome-wide profiling, biomarker...
This $963,000 Project Grant award from the National Institute of Standards and Technology (NIST) under the Congressionally-Identified Projects program (CFDA 11.617) will fund the acquisition of four pieces of specialized research equipment at Nova Southeastern University in Fort Lauderdale, FL. The instruments, including a Seahorse XF24 and Oroboros Oxygraph 2K, a fluorescence microscope, a NanoString nCounter and prep station, and a CODEX digital spatial profiler, will be used to advance new...
This $435,054 federal Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) supports research and development of a solid-state nanopore-based point-of-care nucleic acid testing device. The award aims to address key challenges in translating solid-state nanopore sensors to practical settings, including reproducible size control, introducing specificity, prolonged sensing time at low analyte concentrations, and integrated sample preparation. The research...
The National Human Genome Research Institute (NHGRI), under the Human Genome Research Federal Grant Program (CFDA 93.172), awarded a $384,418 Project Grant to Xgenomes Corp. on September 25, 2024 to develop a revolutionary DNA sequencing platform. The project aims to create a super-resolution single-molecule sequencing technology that can read short sequence "words" rather than individual nucleotides, enabling one or more orders of magnitude improvements in accuracy and cost over...
The federal Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) provides $1,507,500 to the University of Massachusetts Medical School (UMass Medical) to expand the capabilities of third-generation DNA/RNA sequencing technologies. The project aims to generate rapid and cost-effective training libraries to allow for direct detection of common DNA damage and RNA modifications, enabling innovative...
Sequegenics LLC received a $251,073 Project Grant award from the National Science Foundation Division of Industrial Innovation under the Engineering federal grant program (CFDA 47.041). The grant supports development of low-cost and scalable methods for creating genomic databases using long-read next-generation DNA sequencing technologies. This aligns with the program's goals of fostering innovation in engineering research. The one-year project period runs from August 1, 2021 through July 31,...
This Project Grant award from the National Institutes of Health (NIH) Research Infrastructure Programs (CFDA 93.351) provides $1,035,125.00 to the Dana-Farber Cancer Institute (DFCI) to acquire a NovaSeq X Plus high-throughput DNA sequencing system. This instrument will be integrated into DFCI's Molecular Biology Core Facilities (MBCF) to expand their genomics services, including whole genome sequencing, methylation profiling, single-cell genomics, and spatial transcriptomics. The increased...
This federal Project Grant award from the National Cancer Institute (NCI), under the Cancer Detection and Diagnosis Research program (CFDA 93.394), provides $400,000 in funding to Electronic Biosciences, Inc. to develop a novel nanopore-based sequencing approach capable of accurately characterizing repetitive DNA sequences. The project aims to address limitations of current sequencing-by-synthesis methods in accurately sequencing genomic repeats, which are known to harbor variations associated...
The National Institute of Standards and Technology (NIST) awarded a $250,000 Project Grant (CFDA 11.609 - Measurement and Engineering Research and Standards) to the HudsonAlpha Institute for Biotechnology to develop a cybersecurity laboratory focused on securing genomic data processing. The project will involve creating use cases, environments, and technologies for genomic laboratories; conducting research, analysis, testing, and evaluation; and providing educational training on protecting...