Project Grant R21EY039032
- Federal Project Grant Award Summary The University of Rochester received a $243,672 Project Grant from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867), awarded May 1, 2026, with completion targeted for August 31, 2028. The research project investigates the spatial and temporal dynamics of neural interactions underlying attention-related enhancement and suppression of visual processing. The study addresses how visuospatial attention filters incoming sensory...
- Federal Project Grant Award Summary The University of Rochester received $264,250 in federal funding from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) for a project titled "Precise Opto- and Chemo-Genetic Inactivation of Cortico-Cortical Projection Pathways in a Non-Human Primate Model." The award, effective May 5, 2026, and scheduled for completion by...
- Federal Project Grant Award Summary Award Details: The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded the University of Chicago a Project Grant of $929,806 on September 30, 2025, with an ultimate completion date of September 29, 2027. Research Deliverables: This award funds research on synaptic development of the retinogeniculate pathway—the neural circuit connecting the eyes to the brain. The research employs newly developed technology to directly observe...
- Federal Project Grant Award Summary New York University received a $140,184 Project Grant from the National Eye Institute under the Vision Research program (CFDA 93.867), awarded July 1, 2026, with completion scheduled for June 30, 2028. This K99/R00 career development award funds research to decode the molecular and developmental mechanisms underlying precise visual map formation in the fruit fly (Drosophila melanogaster). The project delivers three integrated research aims: (1) examining how...
- Federal Project Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded a Project Grant of $127,785 to the University of California, San Diego on September 15, 2025, with a completion date of December 31, 2025. This research project investigates the neural mechanisms underlying active vision in freely moving marmosets using innovative head-mounted eye-tracking technology coupled with simultaneous neural recording from the visual cortex....
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $127,718 Project Grant award from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) on December 21, 2025, with a completion date of April 30, 2028. The award funds research on neural mechanisms of visuomotor transformations in larval zebrafish, specifically investigating how the vertebrate brain transforms continuous visual motion information into discrete motor...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded $896,500 under the Vision Research program (CFDA 93.867) to The Research Foundation For The State University of New York, operating as Upstate Medical Center, for a project grant commencing September 1, 2025, and concluding August 31, 2027. The award funds research to characterize the transcriptional dynamics and nuclear mobility of the CRX (cone-rod homeobox) homeodomain transcription factor in photoreceptor cells. The...
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded The Methodist Hospital Research Institute a $224,100 Project Grant under the Vision Research program (CFDA 93.867) effective June 1, 2026, through May 31, 2029. The award funds research investigating the role of cortical connections to higher-order thalamic nuclei in visual decision-making in nonhuman primates. The project employs a novel methodology using focused ultrasound to non-invasively open the blood-brain...
- Federal Grant Award Summary Rochester Institute of Technology received a $143,569 Project Grant from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) for the period July 1, 2025 through June 30, 2029. The award supports fundamental research to establish the multi-component phase diagram and statistical-thermodynamic molecular basis of concentrated, aqueous eye lens crystallin protein mixtures. This research directly addresses cataract disease, the leading cause of...
- Federal Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $143,031 to the University of California, Berkeley on December 4, 2025, with a completion date of May 31, 2028. This Project Grant funds computational modeling research investigating the role of spatial phase in the selectivity and invariance of neuronal responses in primary visual cortex (V1) and secondary visual cortex (V2) when processing intermediate-level features in...
The University of Rochester received a $415,875 Project Grant award from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867), effective July 1, 2026 through June 30, 2028. This R21 exploratory grant funds research to develop and validate novel methodologies for targeting and silencing layer-specific frontal feedback pathways in the primate brain, with particular focus on feedback circuits between the frontal eye field (FEF) and middle temporal area (MT) of visual cortex. The award supports the creation of critical research tools and technologies that will enable future investigation into how these distinct neural pathways contribute to active visual behavior, including pre-saccadic attention, saccadic suppression, and visual remapping. The funded research leverages advanced techniques in common marmoset neuroscience, including ultrasound-guided fetal intraventricular viral injection for layer-specific gene delivery, retrograde viral injection for projection-specific neuron targeting, bidirectional optogenetic tools for reversible neural control, and laminar electrophysiology during visual tasks. Deliverables include validated methods for selectively silencing FEF-to-MT feedback neurons at distinct temporal windows during eye movements and confirmation of pathway specificity and efficacy. These methodological developments are designed to establish a foundation for a subsequent R01 grant that will comprehensively test the hypothesis that superficial-layer FEF neurons mediate top-down attentional signals while deep-layer neurons convey motor efference copy for predictive visual coding.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $415.9k | 7/1/26 |