Project Grant K99EY038936
- Federal Grant Award Summary New York University School of Medicine received a $285,498 Project Grant award from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867), effective September 30, 2025 through August 31, 2027. This grant supports basic research investigating the mechanisms of corneal lens development using Drosophila (fruit fly) as a model organism. The research leverages the fly's extensive genetic toolkit and 70% genetic conservation with humans to...
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded a $896,500 Project Grant to The Research Foundation For The State University of New York (operating as Upstate Medical Center) under the Vision Research program (CFDA 93.867), effective September 1, 2025 through August 31, 2027. The research project, titled "YKI-MITF-ECM Regulation of Eye Progenitor Epithelium Morphology," investigates the molecular mechanisms governing eye development and congenital eye...
- Grant Award Summary The University of California, Los Angeles received a $114,789 Project Grant from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867), effective July 1, 2026 through June 30, 2028. This award funds basic neuroscience research investigating the neural mechanisms that drive saccadic eye movements—rapid gaze shifts essential for vision and object tracking. The research employs the fruit fly (Drosophila) as a model organism to elucidate how the brain...
- Federal Project Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $249,000 to The Regents of the University of Colorado (performing at the Los Angeles campus) on August 15, 2026, with completion scheduled for July 31, 2029. This Project Grant funds independent research investigating the molecular determinants of synaptic specificity underlying visuomotor transformations. The research establishes a developmental framework linking graded...
- Federal Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $125,954 to the University of California, Berkeley for a two-year Project Grant (July 1, 2026 – June 30, 2028) to conduct fundamental research on the molecular mechanisms underlying synaptic specificity in the retinal direction-selective circuit. The research addresses how neurons form precise synaptic connections during development and investigates the relevance of these...
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded $130,182 under the Vision Research program (CFDA 93.867) to The Regents of the University of California, San Francisco for a two-year project running from April 1, 2026 through March 31, 2028. This Project Grant funds fundamental neuroscience research investigating how neurons in the primary visual cortex (V1) integrate bottom-up sensory information from the eyes and top-down predictive information from higher brain...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded $896,500 under the Vision Research program (CFDA 93.867) to The Research Foundation For The State University of New York, operating as Upstate Medical Center, for a project grant commencing September 1, 2025, and concluding August 31, 2027. The award funds research to characterize the transcriptional dynamics and nuclear mobility of the CRX (cone-rod homeobox) homeodomain transcription factor in photoreceptor cells. The...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $127,718 Project Grant award from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) on December 21, 2025, with a completion date of April 30, 2028. The award funds research on neural mechanisms of visuomotor transformations in larval zebrafish, specifically investigating how the vertebrate brain transforms continuous visual motion information into discrete motor...
- Federal Project Grant Award Summary Award Details: The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded the University of Chicago a Project Grant of $929,806 on September 30, 2025, with an ultimate completion date of September 29, 2027. Research Deliverables: This award funds research on synaptic development of the retinogeniculate pathway—the neural circuit connecting the eyes to the brain. The research employs newly developed technology to directly observe...
- Federal Project Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded a Project Grant of $127,785 to the University of California, San Diego on September 15, 2025, with a completion date of December 31, 2025. This research project investigates the neural mechanisms underlying active vision in freely moving marmosets using innovative head-mounted eye-tracking technology coupled with simultaneous neural recording from the visual cortex....
New York University received a $140,184 Project Grant from the National Eye Institute under the Vision Research program (CFDA 93.867), awarded July 1, 2026, with completion scheduled for June 30, 2028. This K99/R00 career development award funds research to decode the molecular and developmental mechanisms underlying precise visual map formation in the fruit fly (Drosophila melanogaster). The project delivers three integrated research aims: (1) examining how the temporal sequence of photoreceptor neurogenesis contributes to spatial targeting in early visual circuits; (2) investigating how dorsal-ventral positional cues and planar cell polarity signaling establish region-specific connectivity; and (3) exploring how retinotopic organization is interpreted by higher-order visual neurons and how disruptions alter visually guided behavior. The research employs advanced methodologies including single-cell transcriptomics, high-resolution microscopy, circuit mapping tools (trans-TANGO, GRASP), and behavioral analysis. Beyond basic neurodevelopmental insights, the award integrates structured career development training in scientific writing, mentorship, and leadership. The findings are expected to provide mechanistic understanding of how spatial information is encoded and transmitted during neural circuit assembly, with translational relevance to neural connectivity disorders including amblyopia, autism spectrum disorder, and schizophrenia. This award exemplifies the National Eye Institute's mission to drive innovative research understanding the visual system and prevent vision-related diseases through competitive, peer-reviewed grants to academic research institutions.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $140.2k | 6/23/26 |