Project Grant R21EY038073
- The U.S. National Eye Institute (NEI) awarded a $2,294,505 Project Grant to the Massachusetts Institute of Technology (MIT) to research how retinal silencing can restore synaptic strength in the visual cortex of adults with amblyopia, a prevalent form of visual disability. The funding, awarded on September 1, 2025, will support a 4-year research project with an ultimate completion date of June 30, 2029. The research aims to uncover the mechanisms behind how temporary retinal anesthesia enables...
- The National Eye Institute (NEI) awarded a $437,959 Project Grant to Oregon Health & Science University (OHSU) under the NEI's Vision Research federal grant program (CFDA 93.867) to develop, evaluate, and validate large language models (LLMs) for studying amblyopia treatment, adherence, and outcomes using real-world electronic health record (EHR) data. The project aims to enable more research on amblyopia, a common pediatric eye problem, as well as the development of clinical decision...
- The National Eye Institute (NEI) awarded a $479,417 Project Grant under the Vision Research federal grant program (CFDA 93.867) to the University of Florida to conduct a longitudinal study on the development of infant visuocortical function and its relationship to cognitive outcomes. The 5-year project aims to: Characterize infant visuocortical function and developmental trajectories using measures such as visual evoked potentials, steady-state visual evoked potentials, electroencephalography,...
- The National Eye Institute (NEI) awarded a $448,250 project grant under their Vision Research federal grant program (CFDA 93.867) to The Research Foundation for the State University of New York, operating as Upstate Medical Center. The funding supports a 2-year research project titled "YKI-MITF-ECM Regulation of Eye Progenitor Epithelium Morphology" that will explore the role of the Hippo signaling pathway, the transcription factor MITF, and extracellular matrix in the development...
- The National Eye Institute (NEI) awarded a $431,750 Project Grant to the University of Houston System to conduct research on the mechanisms of scarless corneal wound healing in Acomys cahirinus (African spiny mice) compared to Mus musculus (common house mice). The research, funded under the NEI's Vision Research program (CFDA 93.867), aims to establish whether the African spiny mice can regenerate corneal tissue without scarring following an alkali burn injury and to characterize the...
- This $464,903 federal Project Grant awarded by the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) will support research at the University of Chicago to investigate how neuronal connections form in the retinogeniculate pathway during childhood development. The researchers will focus on understanding how neurons in the visual system make the correct connections, and how disruptions like closing one eye can impact this process. The goal is to gain insights into how...
- The National Eye Institute (NEI) awarded a $421,136 Project Grant to the University of Maryland, College Park under the Vision Research federal grant program (CFDA 93.867) to explore a novel approach for correcting ocular opacities and enabling high-resolution fundus imaging. The 2-year project aims to demonstrate that neural-network based wavefront shaping can optically correct for ocular opacities, which degrade the performance of optical imaging techniques for the posterior segment of the...
- The National Eye Institute awarded Emory University a $391,250 Project Grant under the Vision Research federal grant program (CFDA 93.867) to study the influence of visual input on neuronal signaling in myopia. The five-year project, running from July 1, 2025 to June 30, 2030, aims to increase understanding of the visual pathways that regulate myopia development. The research will use single-cell electrophysiology to investigate how experimentally-induced myopia or exposure to myopia-inducing...
- This federal Project Grant award from the National Eye Institute (CFDA 93.867 Vision Research) provides $441,375.00 to The Regents of the University of California, Berkeley to explore pharmacological interventions for slowing the progression of myopia (nearsightedness) using a guinea pig animal model. The funded research will investigate the efficacy of topical treatments combining levodopa-carbidopa and atropine-levodopa-carbidopa in inhibiting defocus-induced myopia, and explore the underlying...
- The National Eye Institute (NEI) awarded a $482,312 Project Grant to Trustees of Boston University to support research aimed at "Testing a Dynamic Spatiotemporal Normalization Framework for Human Vision." The funding is part of the NEI's Vision Research program (CFDA 93.867), which supports comprehensive research to understand, prevent, and treat vision-related conditions and diseases. The project will develop and test a new computational model of how the visual system processes...
The National Eye Institute (NEI) awarded a $418,388 Project Grant to The Johns Hopkins University to establish the ferret as a new animal model for studying amblyopia, the leading cause of poor vision in infants and children. The project, funded under the NEI's Vision Research program (CFDA 93.867), aims to better understand deficits in higher visual functions associated with amblyopia and explore whether existing treatments can overcome these issues. The work will focus on developing a robust protocol for inducing amblyopia in ferrets, which have a visual system similar to primates, and leveraging the ability to test larger cohorts of ferrets compared to primates. By establishing the ferret as an amblyopia model, this research seeks to advance the understanding and potential treatment of this vision-impairing condition.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $418.4k | 8/14/25 |