Project Grant R21EY036585
Award Date
9/30/24
Completion Date
9/29/26
Dollars Obligated
$441K
Federal Agency
National Eye Institute
Federal Grant Program
93.867
Assistance Type
Project Grant
Place of Performance
Berkeley, CA 94720, USA
Similar Awards
The National Eye Institute (NEI) has awarded a $494,418 Project Grant (CFDA 93.867 Vision Research) to the University of Alabama at Birmingham (UAB) to conduct research on myopia and the visual environment. The project aims to: Determine the anti-myopia effectiveness of various real-world visual scenes to understand how differences between natural and man-made environments may impact eye growth and development of myopia. Develop an improved and safer repeated low-level red light therapy to...
The National Eye Institute (NEI) awarded a $210,534 Project Grant under the Vision Research program (CFDA 93.867) to Legacy Emanuel Hospital & Health Center. The grant supports a study to investigate the relationship between cellular, molecular, and structural alterations in the optic nerve head (ONH) and the development of juvenile myopia using a tree shrew model. The research aims to assess changes in axonal health, myelin, and immune cell infiltration in the ONH, and correlate these...
The National Eye Institute (NEI) awarded a $816,750 Project Grant (Federal Grant Program CFDA 93.867 - Vision Research) to the University of Alabama at Birmingham (UAB) to pilot test a novel wavelength-based method for controlling childhood myopia. The project aims to determine the efficacy of amber contact lens wear for up to four hours per day in slowing myopia progression and axial elongation in 40 myopic children aged 8 to 13 years. This pilot "proof-of-concept" study will test the...
The National Eye Institute (NEI) awarded a $433,125 federal Project Grant (CFDA 93.867 - Vision Research) to The Ohio State University to leverage data from the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) study to address critical clinical questions in myopia control. The funded research aims to analyze axial length data to determine whom to treat and whether myopia control treatments are beneficial, assess the effects of time spent outdoors and sports...
This $148,568 Project Grant award from the National Eye Institute (CFDA 93.867 Vision Research) to Emory University supports research to investigate the role of scleral fibroblasts in refractive development and myopia. The research aims to identify characteristics of scleral fibroblasts that contribute to successful refractive development, and then compare those to changes observed in mouse models of myopia induced by lens wear or retinoic acid exposure. This work will help elucidate the role of...
The National Eye Institute (NEI) awarded a $606,092 Project Grant (CFDA 93.867 Vision Research) to the University of California, Berkeley to investigate the preferred retinal locus (PRL) that develops in individuals with central vision loss due to macular diseases such as age-related macular degeneration (AMD). The project aims to understand the mechanism underlying PRL development, its structural properties and functional capabilities, and whether vision at the PRL can be optimized through...
The National Eye Institute (NEI) awarded a $491,466 Project Grant under the Vision Research federal grant program (CFDA 93.867) to The Regents of the University of California, San Francisco (UCSF) to develop a novel, non-invasive, and sensitive measure of retinal dysfunction. The goal is to expand on preliminary data showing that a visually-evoked compensatory behavior known as the optokinetic reflex (OKR) can detect graded cone loss in mice. The project aims to develop OKR-inducing stimuli...
The National Eye Institute (NEI) awarded a $360,897 Project Grant (CFDA 93.867 - Vision Research) to Human Cell Co., a for-profit biotechnology research company, with a performance period from September 30, 2024 to August 31, 2025. The grant supports the development and evaluation of a novel combination therapy for glaucoma, involving topical administration of a proprietary nerve growth factor (NGF) mutein, HC201, in conjunction with oral nicotinamide (NAM) supplementation. The key objectives...
The National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), awarded a $153,512 Project Grant to Oregon Health & Science University (OHSU) to support research on the structural basis of selective inhibition of gap junction channels involved in vision. The project aims to leverage recent advances in cryo-EM and fragment antigen-binding (Fab) technologies to deconvolute the mechanism of inhibitory action against native heteromeric gap junctions....
This federal Project Grant award from the National Eye Institute (NEI), part of the Vision Research program (CFDA 93.867), provides $1,330,026 to develop two new mouse models of geographic atrophy, the advanced form of dry age-related macular degeneration (AMD). The goal is to use these models to evaluate the efficacy of a novel antioxidant therapeutic, deuterated docosahexaenoic acid (D-DHA), in protecting the retinal pigment epithelium from degeneration. The research, conducted by The Trustees...