Project Grant R21EY037039
- This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) provides funding to researchers at the University of California, San Francisco (UCSF) to study the neural mechanisms underlying visual processing and behavior after photoreceptor degeneration. The $237,588 award, spanning June 2025 through December 2027, will leverage the vertical optokinetic reflex (OKR) - a visual behavior that tracks global motion - to investigate how cone degeneration disrupts noise...
- This $240,750 federal Project Grant award from the National Eye Institute's Vision Research program (CFDA 93.867) aims to investigate the role of neural-glial-vascular signaling in the development of the eye's vasculature. The research has two main objectives: 1) Characterizing vasculature development and how it is altered in mice with modified retinal waves, using quantitative approaches and live imaging, and 2) Establishing the maturation of the glial-vascular unit through immunofluorescence...
- This Project Grant award from the National Eye Institute's Vision Research program (CFDA 93.867) provides $179,964 to the University of California, Irvine (UCI) to develop innovative biomarkers for optic neuropathies using deep learning-based analysis of optical coherence tomography (OCT) imagery. The project aims to overcome limitations of current OCT-based diagnostics by employing advanced computational techniques like deep learning, neural fields, and geometric modeling to enhance the...
- This $464,903 federal Project Grant awarded by the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) will support research at the University of Chicago to investigate how neuronal connections form in the retinogeniculate pathway during childhood development. The researchers will focus on understanding how neurons in the visual system make the correct connections, and how disruptions like closing one eye can impact this process. The goal is to gain insights into how...
- This $688,882 Project Grant awarded by the National Eye Institute (NEI) under the Vision Research federal grant program (CFDA 93.867) supports a multidisciplinary research project on the neuronal computations underlying rapid and flexible visual categorical decision-making in humans. The project employs a combination of large-scale neuronal population recording techniques and theoretical modeling to investigate the coordinated activity within and between brain regions like the posterior parietal...
- This Project Grant award, provided by the National Eye Institute (CFDA 93.867 - Vision Research), is supporting research at The University of Iowa to enable the production of autologous (patient-derived) cell therapies for treating inherited retinal degenerative blindness. The $618,600 award, effective from March 1, 2025 to February 28, 2030, aims to address key challenges in the manufacturing of these personalized cell therapies, such as assessing retinal differentiation capacity and...
- This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) supports the development of a novel, noninvasive, and sensitive diagnostic method to measure retinal dysfunction. The $491,466 award will fund research at the University of California, San Francisco (UCSF) from January 1, 2025 to December 31, 2026. The project aims to create a scalable diagnostic tool that can detect the earliest signs of retinal diseases like diabetic retinopathy and retinitis pigmentosa,...
- This federal Project Grant award of $460,500 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) is aimed at developing novel bioprinting methodologies for the production of human stem cell-based organoids. The key objectives are to: 1) Create a customized bioink formulation using proteins, polysaccharides, and functionalized nanoparticles to foster the...
- This $231,000 Project Grant award from the National Eye Institute (NEI), under the federal Vision Research program (CFDA 93.867), will fund the development of a generalized deep learning platform to improve the objectivity, reproducibility, and accuracy of quantifying and assessing experimental autoimmune uveitis (EAU) - a valuable animal disease model for studying human uveitis. The project aims to generate high-quality, well-annotated multi-modal datasets from three independent research...
- This Project Grant award of $232,500 from the National Eye Institute (CFDA 93.867 - Vision Research) supports research at The Johns Hopkins University to investigate the use of micro-stimulation of mid-level and higher-level visual cortex as a prosthetic strategy for restoring 3D object vision. The research aims to demonstrate that micro-stimulation of specific V4 neuron clusters that encode 3D geometric shape fragments can causally influence 3D shape perception in macaque monkeys. If...
This $437,250 Project Grant award from the National Eye Institute's Vision Research federal grant program (CFDA 93.867) aims to develop an integrated platform that combines 3D bioprinting, optogenetic stimulation, multi-electrode array (MEA) recording, and real-time fluorescence imaging to create a "visual-circuit-on-a-chip" for evaluating neural activity in stem cell-derived retinal disease models. The project, awarded to the University of California, San Diego, seeks to address challenges in accurately modeling retinal degenerative disorders by leveraging recent advances in tissue engineering, 3D bioprinting, and human induced pluripotent stem cell technologies. The integrated platform will enable patterning 3D retinal tissue constructs and probing their electrical activity, with the goal of elucidating the relationships between cell physiology, electrochemical signaling, and higher-level visual processing. The award period runs from September 1, 2025 to August 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 9/22/25 | ||
| Not listed | $437.3k | 8/15/25 |