Project Grant R21EB039771
- The National Institute of Biomedical Imaging and Bioengineering awarded the Trustees of Boston University $232,550 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a mid-infrared photothermal fiber probe for label-free imaging and biomolecular composition analysis in endoscopic applications. The project will develop a fiber-based probe that integrates mid-infrared photothermal imaging with...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of California, Santa Barbara $582,137 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop electrochemical aptamer-based sensors for long-duration, real-time molecular measurements in living tissue. The research aims to extend the in vivo operational lifespan of electrochemical aptamer-based sensors beyond their...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Cincinnati Sponsored Research Services Division $398,400 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop chemically-modified aptamer electrochemical sensors for ultra-sensitive biomonitoring. The research advances continuous biochemical monitoring technology to detect biomarkers at picomolar-to-nanomolar...
- The National Institute of General Medical Sciences awarded The General Hospital Corporation (Massachusetts General Hospital) $444,000 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop secreted genetically encoded fluorescent biosensors for in vivo extracellular imaging. The project will create a toolkit of biosensors across four research areas: imaging extracellular matrix structures by conjugating fluorescent proteins to lectins and...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of California, Santa Barbara $1,189,496 on April 10, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop real-time, seconds-resolved measurements of amino acid homeostasis using electrochemical aptamer-based (EAB) sensors. The project will adapt EAB sensor technology—a platform invented by UCSB researchers—to measure plasma...
- The National Institute of Biomedical Imaging and Bioengineering awarded Trustees of Boston University $641,300 on May 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286, assistance type Project Grant) to develop next-generation chemoproteomic affinity-based peptide probes (CAFBPs) for targeted profiling of oncogenic kinase activity in circulating tumor cells. The project addresses technical barriers in isolating and...
- The National Science Foundation (NSF) awarded a three-year, $449,999 Project Grant under their Engineering program (CFDA 47.041) to the University of Cincinnati to develop an implantable biosensor platform that can continuously monitor various biomarkers in the body for over a year. The project aims to create a new class of long-lasting aptamer-based sensors protected by robust porous oxide coatings, which would enable the first practical implantable monitoring system for managing chronic...
- Federal Project Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded the Trustees of Boston University a Project Grant of $613,124 under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) for the period August 15, 2025, through July 31, 2028. The project delivers the development and demonstration of Quantitative Phase Imaging Meta-Sensors (PIMSs)—advanced optical imaging sensors that...
- Federal Project Grant Award Summary Boston University received a $450K Project Grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041) on November 1, 2025, for development and validation of wireless, free-floating biosensors designed for in-situ microbial monitoring within industrial fermentation environments. The award, which extends through October 31, 2027, supports the development of a...
- The National Institute of General Medical Sciences awarded the Regents of the University of Michigan $411,475 under the Biomedical Research and Research Training program (CFDA 93.859) on September 1, 2026, to engineer a multiplexed biomaterial-based bioluminescent biosensor platform for real-time sepsis diagnosis and precision immunotherapy guidance. The recipient will develop a rapid ex vivo biosensor using biomaterial-immobilized complementation antibody pairs to dynamically sense proteomic...
The National Institute of Biomedical Imaging and Bioengineering awarded the Trustees of Boston University $245,250 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop living microbial sensors for continuous biochemical monitoring. The project will engineer and validate a self-renewing cell cartridge that maintains bacterial viability for multiple weeks using passive nutrient diffusion and division-driven cell flux, confining cells safely while permitting biomarker molecules to diffuse for sensing. The cartridge will integrate genetic reporters with temperature, pH, and oxygen sensors to establish a normalization and calibration framework ensuring quantitative accuracy across urine and saliva matrices. The resulting steady-state, reusable living sensor platform will operate without pumps or continuous power, supporting wearable, ingestible, or in-toilet devices for continuous health monitoring in chronic conditions including kidney disease, metabolic disorders, and inflammation. Performance occurs in Boston, Massachusetts. The award period runs from September 1, 2026, through June 30, 2029. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $245.3k | 8/27/26 |