Project Grant R21EB036894
- Summary The California Institute of Technology received a $1.46M Project Grant from the National Institute of Biomedical Imaging and Bioengineering under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), awarded August 1, 2025, with a completion date of July 31, 2029. The grant funds research to miniaturize time-resolved fluorescence (TRF) and fluorescence lifetime imaging (FLIM) measurements using entangled photons and on-chip...
- The National Institute of Biomedical Imaging and Bioengineering awarded the Trustees of Boston University $232,550 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a mid-infrared photothermal fiber probe for label-free imaging and biomolecular composition analysis in endoscopic applications. The project will develop a fiber-based probe that integrates mid-infrared photothermal imaging with...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of California, Santa Barbara $582,137 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop electrochemical aptamer-based sensors for long-duration, real-time molecular measurements in living tissue. The research aims to extend the in vivo operational lifespan of electrochemical aptamer-based sensors beyond their...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of California Santa Cruz $234,750 on August 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a de novo binder-luciferase platform for multiplexed protein detection in Western blots and lateral flow assays. The project will replace antibody-based detection reagents with computationally designed, thermostable de novo...
- The National Institute of General Medical Sciences awarded $430,109 to The Regents of the University of California, operating Lawrence Berkeley National Laboratory, on June 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop deeply subwavelength near infrared imaging technology using avalanching nanoparticles. The project addresses fundamental limitations of live-cell optical microscopy by creating avalanching nanoparticles (ANPs) that upconvert incident...
- The National Institute of Biomedical Imaging and Bioengineering, a component of the Department of Health and Human Services National Institutes of Health, awarded $184,063 to the University of Texas at San Antonio on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The award funds development of forced-dimerization activated photoacoustic aptamer switch sensors (FDA-PASS), optical probes designed to enable...
- The National Institute of Biomedical Imaging and Bioengineering awarded The Regents of the University of California, San Francisco $592,108 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). UCSF will develop and validate stress-sensing microparticles that integrate deformable polymers and mechanomagnetic resonance nanotransducers to enable real-time monitoring of in vivo tissue mechanics with...
- The National Institute of Biomedical Imaging and Bioengineering awarded Rensselaer Polytechnic Institute $366,006 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a simulation-based inference framework that transforms functional near-infrared spectroscopy (fNIRS) data analysis through artificial intelligence. The project delivers a biophysically detailed simulator integrating realistic models...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB), part of the Department of Health and Human Services National Institutes of Health, awarded the University of Texas at Arlington $339,676 on August 18, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop light-responsive osmium compounds as metallo-reagents for biomedical imaging and photoactivation. The project develops osmium-based...
- Federal Grant Award Summary The University of California Santa Cruz received a $412,276 Project Grant from the National Institute of Biomedical Imaging and Bioengineering under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), awarded September 1, 2025, with completion targeted for August 31, 2027. This award supports the development and validation of an optofluidic biosensor integrating a waveguide spectrometer for spectral...
The National Institute of Biomedical Imaging and Bioengineering awarded Scripps Research Institute $276,000 on August 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop and validate novel fluorescence resonance energy transfer (FRET) sensing methods that leverage entangled photons for biomedical applications. The project will explore quantum sensing technologies to advance FRET-based detection across biological scales, with proof-of-principle applications in sensing biomolecule binding and conformation as well as membrane properties. The work builds on the institute's existing expertise in high-sensitivity fluorescence methods combined with recent developments in quantum sensing. Performance occurs in La Jolla, California, with a period of performance from August 1, 2026, through July 31, 2028. This is a Project Grant, the assistance type supporting hypothesis- and technology-driven research for discovery, design, development, validation, and application of biomedical imaging and bioengineering technologies. The research aims to establish foundational steps for expanded biomedical sensing applications with implications for human health.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $276.0k | 7/21/26 |