Project Grant R43DK143794
- This Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to develop a novel kidney-draining lymph node-targeted nanotherapeutic for treating crescentic glomerulonephritis (CGN), a severe immune-mediated kidney condition. The $2,466,907 award to Brigham & Women's Hospital Inc., a subsidiary of Partners Healthcare System...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $343,650 to Rush University Medical Center to conduct research on Hodgkin's lymphoma-induced nephrotic syndrome. The research aims to investigate how cytokines and soluble proteins released by Hodgkin Reed-Sternberg cells trigger glomerular injury and albuminuria in mice with a...
- This $108,294 Project Grant was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant recipient is The Medical University of South Carolina (MUSC), which will use the funding to identify novel glycomic biomarkers that can be detected in urine to monitor disease progression and predict treatment response in lupus nephritis, a serious kidney disease that affects...
- The Defense Health Agency awarded a $999,972 Project Grant to The Feinstein Institutes For Medical Research in Plandome, NY to study urine macrophages in lupus nephritis and shed light on kidney disease processes. This award is part of the Military Medical Research and Development program (CFDA 12.420), which supports advanced biomedical research to transform healthcare for military service members, veterans, and the public. The research aims to develop a better understanding of the...
- This federal Project Grant award, in the amount of $531,999.00, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award is supporting research focused on understanding the role of alternative splicing in the proximal tubules of the kidney and its relationship to the progression of diabetic kidney disease. The research will investigate how diabetes...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $153,512 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Leland Stanford Junior University. The grant will fund research to characterize the renal immune microenvironment in antibody-mediated rejection (ABMR) of kidney transplants in order to develop improved diagnostics and predict treatment response. The research will utilize advanced imaging mass cytometry to profile...
- This $108,486 Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to identify novel immune markers associated with obesity-driven diseases. The objective is to utilize novel tools to study the inter-organ communication pathway between the intestine and adipose tissue immune cells. The research leverages a Cre-inducible...
- This Project Grant award for $194,380, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to study the role of the protein LIM-nebulette in maintaining the structural integrity of podocytes, which are specialized kidney cells. The research project, conducted by the Icahn School of Medicine at Mount Sinai, will utilize a novel mechanical stretch platform and...
- This $659,358 Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research at Beth Israel Deaconess Medical Center, Inc. (Bidmc) investigating the genetic and biological mechanisms underlying kidney disease associated with APOL1 risk variants, particularly focused on the relationship between APOL1 gene dose and kidney...
- This Project Grant award, titled "Revolutionizing Renal Histopathology: Integrating Multiplexed Immunofluorescence and ML/AI Image-Based Biomarkers for Precision Diagnosis and Patient Stratification", is funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The $464,750 award aims to develop an advanced imaging and analysis platform for renal diagnostics,...
This federal Project Grant award of $304,993 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Immunowork LLC, located in Monrovia, CA. The award supports a research project to quantify peripheral blood antigen-specific memory B cells as a new biomarker in patients with PLA2R-associated membranous nephropathy, a common form of nephrotic syndrome. The goal is to develop a flow cytometry-based assay that can detect and quantify circulating PLA2R antigen-specific memory B cells, which are precursors to anti-PLA2R autoantibody production. This research aims to provide crucial immunological information to help assess patient response to immunosuppressive therapies and monitor for early signs of disease relapse. The award period is from Sep 15, 2025 to Aug 31, 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $305.0k | 9/12/25 |