Project Grant R21DA066724
- The National Institute on Drug Abuse awarded the University of Maryland, Baltimore $656,916 on August 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to investigate insular-amygdala conflict processing mechanisms in opioid use disorder relapse prevention. The project, titled "Insular-Amygdala Conflict Processing After Voluntary Abstinence," examines how the anterior insular cortex (AIC) processes conflicting motivations in individuals with opioid use disorder...
- The National Institute on Drug Abuse awarded Johns Hopkins University $198,164 on October 17, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct research examining barriers to medications for opioid use disorder (MOUD) treatment for individuals transitioning from correctional facilities to community settings. The research employs a complex systems approach combining quantitative and qualitative methods. Specific aims include examining the structure and function...
- The National Institute on Drug Abuse awarded The Trustees of Columbia University in the City of New York $1,555,130 on May 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop quantitative evidence informing personalized, sequential medication-for-opioid-use-disorder (MOUD) treatment protocols. The research applies data fusion methodology to synthesize data from seven large MOUD trials conducted by the NIDA Clinical Trials Network, generating evidence-based...
- The National Institute on Drug Abuse awarded the University of Maryland, College Park $183,873 on May 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to support research into implementation strategies for substance use services delivered to rural adolescents. The award funds a K23 project titled "Recovery Opportunities Through Ongoing Treatment Sustainment (ROOTS): A Dynamic Approach to Integrate and Sustain Adolescent Substance Use Services in Rural...
- The National Institute on Drug Abuse awarded the University of Maryland, College Park $107,386 on May 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop a single-session, peer-delivered internalized stigma reduction intervention for individuals with polysubstance use in rural Maryland. The intervention addresses internalized substance use disorder and medication for opioid use disorder stigmas that obstruct treatment engagement, retention, and recovery outcomes...
- The National Institute on Drug Abuse awarded the University of Maryland, College Park $107,090 on February 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to support research mapping how trajectories of perinatal substance use and depression impact neonatal brain development. The research characterizes the longitudinal interplay between perinatal substance use and perinatal depression and examines their combined impact on infant hippocampal volume and growth. The study...
- The National Institute on Drug Abuse awarded University of Wisconsin-Madison a $5.014 million cooperative agreement (UM1DA064515) on September 15, 2025, to conduct a three-arm comparative effectiveness cluster randomized controlled trial evaluating systems change approaches to scaling medications for opioid use disorder (MOUD) across 120 prisons in 12 states through May 31, 2030, under the Drug Use and Addiction Research Programs (CFDA 93.279). The award funds implementation science research...
- The National Institute on Drug Abuse awarded the University of Maryland, Baltimore $1,371,874 under the Drug Use and Addiction Research Programs (CFDA 93.279) on March 15, 2026, to investigate the impact of opioid use disorder on mitochondrial dysfunction among antiretroviral therapy-receiving aging people with HIV. The research addresses a gap in understanding how long-term antiretroviral therapy and opioid use disorder compound inflammaging—a low-grade chronic proinflammatory immune...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $823,809 to the University of Pittsburgh to develop and validate a suite of multidimensional measures of access to Medications for Opioid Use Disorder (MOUD) across U.S. states and the District of Columbia. The primary objectives are to: Create a Small Area Multidimensional MOUD Access (SAMMA) measure suite using public data sources. Validate and...
- The National Institute on Drug Abuse awarded the University of Pittsburgh $701,569 on September 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct research on the use and effectiveness of medications for opioid use disorder in older adults with multimorbidity. The award funds quantitative studies of Medicare and Veterans Health Administration enrollees with diagnosed opioid use disorder and a qualitative study of older adults with opioid use disorder and...
The National Institute on Drug Abuse awarded the University of Maryland, College Park $444,801 on September 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to optimize medications for opioid use disorder (MOUD) expansion across Maryland using data-driven implementation strategies. The project constructs a MOUD access index integrating opioid use disorder prevalence, provider capacity, spatial accessibility, and contextual factors to model need for and access to MOUD. The recipient applies spatial optimization modeling to optimize deployment of three implementation strategies—mobile MOUD services, telehealth-delivered MOUD, and provider training and technical assistance—across Maryland under real-world constraints to maximize population coverage and minimize travel burden for patients. The project evaluates incremental cost-effectiveness of these geo-optimized strategies relative to current service distribution, reporting cost per MOUD initiation, overdose averted, and quality-adjusted life years gained. Performance occurs in College Park, Maryland, with a period of performance through August 31, 2028. The project links geospatial modeling, implementation science, and cost-effectiveness modeling to produce actionable guidance informing MOUD expansion and advances implementation science through integration of spatial analytics and economic evaluation into prospective implementation strategy selection.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $444.8k | 8/21/26 |