Project Grant R21DA061414
Award Date
7/15/24
Completion Date
6/30/26
Dollars Obligated
$239K
Federal Agency
National Institute on Drug Abuse
Federal Grant Program
93.279
Assistance Type
Project Grant
Place of Performance
Pennsylvania, USA
Similar Awards
This $779,969 Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to improve perioperative care for patients with opioid use disorder. The key objectives are to: Prospectively capture patient-reported pain and opioid use data among individuals with opioid use disorder undergoing common surgical procedures, and develop evidence-based prescribing guidelines. Qualitatively assess the perioperative experiences...
This $701,959 Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to improve perioperative care for patients with opioid tolerance in the United States. The key objectives are to: Prospectively capture patient-reported opioid use and pain outcomes among opioid-tolerant individuals undergoing common surgical procedures, and develop a clinical care pathway to optimize outcomes across a network of hospitals...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $295,906 to Addinex Technologies, Inc. to integrate and assess a closed-loop medication management system for opioid pain management in ambulatory patients with extremity fractures being discharged from the emergency department. The project aims to adapt Addinex's existing medication dispensing platform to work within a hospital pharmacy setting,...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), is focused on enhancing pain management for knee replacement patients through an innovative non-invasive and opioid-sparing device. The $416,443 award to NCAP Medical, LLC will fund a randomized placebo-controlled clinical trial to evaluate the use of the "Neurocuple" device as a non-pharmacological postoperative pain relief treatment following...
This $1,534,938 Project Grant awarded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund a randomized controlled trial to evaluate an immersive mindfulness virtual reality (VR) intervention for chronic pain and opioid use disorder (OUD) in opioid treatment programs. The grant will support enrollment and randomization of 185 participants with chronic pain and OUD at opioid treatment programs in the Bronx, New York to receive...
This $1,076,036 federal Project Grant award was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The grant aims to characterize electroencephalography (EEG) signatures in the prefrontal cortex (PFC) following chronic opioid use and modulation of PFC interneurons. Specifically, the research will: Test if individual differences in PFC theta power and PFC interneuron physiology correlate with fentanyl self-administration and...
This $858,600 Project Grant was awarded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to the University of Pittsburgh. The grant aims to identify and validate G protein-coupled receptors (GPCRs) expressed by somatostatin-expressing inhibitory neurons in the prefrontal cortex that could be targeted for developing new treatments for opioid use disorder (OUD). The research will use an unbiased transcriptomics approach to identify...
This $220,668 Project Grant, awarded by the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279), supports the development of a novel opioid adjuvant by Amalgent Therapeutics, Inc. The adjuvant aims to increase the pain-relieving efficacy of opioids, allowing for substantial reductions in opioid doses and mitigating the risks of opioid abuse, tolerance, and ineffectiveness for neuropathic pain. The project will investigate the mechanism of action...
This federal Project Grant award from the National Institutes of Health (CFDA 93.279 - Drug Abuse and Addiction Research Programs) provides $1,105,489 to The Leland Stanford Junior University (Stanford University) to fund research aimed at reducing the risk of persistent postoperative opioid use and opioid use disorder among older adults undergoing inpatient surgery. The key products and services to be delivered under this 2-year grant include: Augmenting an existing dataset that links...
This $159,711 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) supports a study titled "Electrophysiological Dynamics of Acute Opioid Use in Human Reward, Affect, and Pain Pathways." The project aims to investigate how acute opioid administration impacts neural connectivity within brain regions associated with opioid use disorder (OUD), including the amygdala, hippocampus, prefrontal cortex, and pain...