This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $192,780 to The Leland Stanford Junior University to conduct research evaluating the impact of discontinuing medications for opioid use disorder (MOUD) after surgery and identifying predictors and outcomes to guide perioperative care. The key objectives are to: 1) Identify risk factors for MOUD discontinuation after surgery and develop a predictive...
The National Institute on Drug Abuse (NIDA) awarded a $779,969 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to the Regents of the University of Michigan. The grant, with a performance period from September 30, 2024 to July 31, 2029, aims to improve perioperative care for patients with opioid use disorder. The key objectives are to: 1) capture patient-reported pain and opioid use among individuals with opioid use disorder undergoing common surgical procedures,...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $2,398,820.00 to fund research aimed at developing safer opioid analgesics and antagonists with the goal of reducing the adverse effects associated with traditional opioid medications. The key products and services to be delivered under this grant include: Synthesis and in vitro characterization of novel opioid receptor ligands that...
This $701,959 Project Grant award from the National Institute on Drug Abuse (NIDA), under the CFDA program "Drug Use and Addiction Research Programs" (93.279), aims to improve perioperative care for patients with opioid tolerance. The key objectives are to: Capture patient-reported opioid use and pain outcomes among opioid-tolerant individuals undergoing common surgical procedures, and develop a clinical care pathway to optimize outcomes across a network of hospitals in Michigan....
This $238,500 Project Grant awarded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund research to develop a telemedicine-delivered digital cognitive behavioral intervention (DCBI) to decrease opioid use among patients undergoing total knee and hip arthroplasty. The project aims to quantify the opioid-sparing properties of the DCBI, evaluate its effects on reducing preoperative depression, anxiety, and pain catastrophizing,...
The University of California, San Francisco (UCSF) was awarded a $2,041,992 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) on September 15, 2024. The grant will fund a systematic analysis of over 3.1 million internal industry documents obtained through litigation, to assess how opioid manufacturers marketed prescription opioids to patients, healthcare providers, and regulators. The research aims to identify...
This Project Grant award of $598,312 from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will support the integration and assessment of Addinex Technologies, Inc.'s closed-loop medication management system for opioid pain management in ambulatory patients with extremity fractures being discharged from the emergency department. The primary objectives are to: 1) adapt and enhance the Addinex system to align with hospital pharmacy...
This federal Project Grant award of $366,377, provided by the National Institute of Neurological Disorders and Stroke under the Drug Use and Addiction Research Programs (CFDA 93.279), will fund a 5-year institutional postdoctoral training program in clinical pain research focused on maternal and childhood pain at Stanford University. The program aims to bolster the clinical pain research workforce by providing mentorship and training to 5 postdoctoral fellows per year across areas such as...
This $2,542,500 federal Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will support the development of novel econometric research methods to integrate real-world evidence (RWE) data into the analysis of inconclusive randomized controlled trials (RCTs) for opioid use disorder (OUD) treatments. The project aims to create a unified framework for using RWE to supplement RCT findings, particularly for vulnerable...
This Project Grant award for $195,728 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will support research to assess the acceptability and feasibility of using pharmacogenomic (PGx) testing to guide opioid use disorder (OUD) treatment. The key activities include: Identifying barriers and facilitators to implementing a PGx testing protocol for OUD treatment by engaging patients, providers, clinic staff, and administrators...