Project Grant R61DA059168

Award Date 9/1/23
Completion Date 8/31/25
Dollars Obligated $1.1M
Federal Grant Program
93.279
Assistance Type
Project Grant
Place of Performance
California, USA
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This federal Project Grant award from the National Institutes of Health (CFDA 93.279 - Drug Abuse and Addiction Research Programs) provides $1,105,489 to The Leland Stanford Junior University (Stanford University) to fund research aimed at reducing the risk of persistent postoperative opioid use and opioid use disorder among older adults undergoing inpatient surgery.

The key products and services to be delivered under this 2-year grant include:

  1. Augmenting an existing dataset that links surgical case data from the Multicenter Perioperative Outcomes Group (MPOG) registry with Medicare fee-for-service claims data, to enable evaluating the association between perioperative interventions (e.g. intraoperative opioid administration, use of nerve blocks) and long-term opioid-related outcomes.

  2. Demonstrating the feasibility of the dataset integration methods at a single institution and expanding to five additional sites.

  3. Using the enhanced dataset to evaluate the impact of intraoperative and inpatient stay interventions (e.g. reduced opioid use, non-opioid pain management) on persistent postoperative opioid use and opioid use disorder.

  4. Collaborating with stakeholders to incorporate the research findings into clinical guidelines and policy to help guide perioperative decision-making and reduce long-term opioid-related consequences in this high-risk older adult population.

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