Project Grant R01DA058029

Award Date 7/15/24
Completion Date 4/30/29
Dollars Obligated $702K
Federal Grant Program
93.279
Assistance Type
Project Grant
Place of Performance
Michigan, USA
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This Project Grant award by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund research to improve perioperative care for patients with opioid use disorder. The total award of $779,969 will be used to: Prospectively capture patient-reported pain and opioid use data among individuals with opioid use disorder undergoing common surgical procedures, to inform the adaptation of prescribing guidelines. Qualitatively assess the...
This $4.68 million project grant from the National Institute on Drug Abuse, part of the Department of Health and Human Services, will fund research under the Drug Abuse and Addiction Research Programs (CFDA 93.279). The University of Michigan will conduct a prospective cohort study of 400 adults with opioid-involved polysubstance use in Michigan. Researchers will collect detailed weekly data on participants' substance use patterns and motivations over four weeks to understand nuanced profiles...
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This federal Project Grant award for $701,959, funded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to improve perioperative care for patients with opioid tolerance. The key objectives are to:

  1. Prospectively capture patient-reported opioid use and pain outcomes among opioid tolerant individuals undergoing common surgical procedures, and develop a clinical care pathway to optimize outcomes across a network of hospitals in Michigan.

  2. Conduct qualitative interviews with patients, providers, and healthcare leaders to inform the development of a clinical care pathway for perioperative pain management of opioid tolerant patients.

  3. Implement a prospective randomized trial to determine the effectiveness of the care pathway on coordinating care, reducing high-risk prescribing practices, length of stay, readmissions, and optimizing patient-reported pain.

The project will be conducted by the Regents of the University of Michigan from July 2024 through April 2029. This award seeks to address critical knowledge gaps and develop evidence-based interventions to provide safer perioperative care for the growing population of opioid tolerant surgical patients in the United States.

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