Project Grant R21CA297739
- This federal Project Grant award of $676,550 from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) supports research to understand the impact of socioeconomic status (SES) and adversity on hematopoietic cell transplant (HCT) outcomes in pediatric patients with high-risk hematological malignancies. The primary goals are to: 1) quantify the association between donor and recipient SES with pediatric HCT outcomes, and 2) evaluate how donor and recipient SES...
- This federal Project Grant award of $423,500.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to the Regents of the University of Minnesota. The grant supports a 5-year research project focused on quantitatively exploring somatic mutation burdens in normal, non-cancerous mouse tissues across different life stages. The project aims to utilize cutting-edge DNA sequencing technologies and...
- This $726,828 Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) to Northwestern University supports comprehensive research to investigate the role of adverse social-biological interactions in acute myeloid leukemia (AML) disparities. The key objectives are to: 1) develop a neighborhood stress scale and link it to adverse genomic characteristics of AML and clinical outcomes; 2) conduct a prospective study on the effects of self-reported...
- This federal Project Grant award of $204,474, awarded by the National Cancer Institute (CFDA 93.398 Cancer Research Manpower program), is supporting research to define the transition from deep cell quiescence to senescence. The University of Colorado, the awardee, will use time-lapse microscopy and molecular assays to investigate the mechanisms controlling quiescence depth and the relationship between deep quiescence and senescence. The research aims to determine if senescence is a form of...
- This federal Project Grant award of $464,212.00 from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) supports research to characterize the biological mechanisms underlying the pleiotropic effects of genetic variation at the TERT/CLPTM1L locus on cancer susceptibility and aging-related traits. The University of Chicago, the awardee, will integrate large-scale genetic association data, multi-omic quantitative trait loci (QTLs) in stem/differentiating cells, and...
- This federal Project Grant award of $635,033, provided by the National Cancer Institute (CFDA 93.393 Cancer Cause and Prevention Research program), supports research to understand the genetic basis of a newly recognized cancer-prone syndrome caused by long telomere length. The award was granted to The Johns Hopkins University, a leading federal research contractor, to conduct comprehensive investigations into this genetic mechanism driving cancer development, which is distinct from tumor...
- This Project Grant award from the National Cancer Institute (CFDA 93.398 - Cancer Research Manpower) provides $150,878 to the Regents of the University of Minnesota (doing business as the Office of Sponsored Projects Administration) to support research on tissue-resident adaptive CD56bright natural killer (NK) cell responses in cancer. The key objectives are to advance the understanding of the functions of CD56bright "bright-tank" NK cell populations in tumors and identify mechanisms...
- This $1,073,982 National Cancer Institute project grant will fund research at Washington University in University City, Missouri from January 2023 through December 2027 under the Cancer Cause and Prevention Research program (CFDA 93.393). The research aims to document unmet social needs among 300 patient-caregiver dyads where the patient has breast or gynecologic cancer. It will analyze how social needs affect biopsychosocial outcomes for patients and caregivers, including depressive symptoms,...
- This $580,238 federal Project Grant was awarded by the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) to the Regents of the University of Minnesota on January 10, 2025. The grant will fund a 5-year research project to investigate novel blood biomarkers that could predict the early development of hepatocellular carcinoma (liver cancer) in Hispanic individuals infected with the hepatitis B virus. The research aims to develop a non-visual screening approach...
- This Project Grant award of $3,304,237 from the National Institute on Aging (CFDA 93.866 - Aging Research) will support a 40-year longitudinal study examining the links between early life adversity, cumulative life stress, and cellular aging in midlife women and their offspring. The study aims to assess which aspects of life course stress, including childhood, midlife, and cumulative stress, are associated with accelerated cellular aging at age 50. The study will repeat assessments of cell aging...
This federal Project Grant award of $386,612 from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) will support a research project by the Regents of the University of Minnesota to investigate socioeconomic and environmental factors that contribute to accelerated biological aging, cancer risk, and differences in cancer outcomes among middle-aged and older adults. The project will leverage data from two large prospective studies, the Atherosclerosis Risk in Communities (ARIC) study and the Multi-Ethnic Study of Atherosclerosis (MESA), to examine how person-level and neighborhood-level social determinants of health, such as education, economic stability, and social isolation, independently and jointly impact biological aging, cancer incidence, and mortality among cancer survivors. The award period is from August 13, 2025 to July 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $386.6k | 8/11/25 |