Project Grant R21AI194190
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Georgia Research Foundation, Inc. a $228,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period July 1, 2026 through June 30, 2028. The project, titled "Parasite Glycosylphosphatidylinositol Libraries: Expanding the Toolbox for Parasite Glycobiology," focuses on developing enzymatic pipelines and modular...
- Federal Grant Award Summary The University of Georgia Research Foundation, Inc. received a $650,020 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2030. This five-year research initiative will deliver investigative services focused on elucidating the mechanisms underlying memory regulatory T cell (mTreg)-mediated protection in...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $451,000 to the University of California, San Francisco under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 15, 2025, with completion scheduled for July 31, 2027. This Project Grant supports the development and application of high-resolution phage immunoprecipitation sequencing (PhIP-Seq) arrays designed to comprehensively evaluate antibody responses to...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Georgia Research Foundation, Inc. a Project Grant totaling $415,250 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 21, 2025, with completion targeted for July 31, 2027. This research initiative addresses critical gaps in understanding gram-negative bacterial resistance mechanisms by investigating the feedback signaling system that...
- Federal Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant of $107,542 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period September 1, 2025, through August 31, 2027. The award supports investigator-initiated biomedical research examining the differential sorting and trafficking mechanisms of Plasmodium falciparum secreted proteins, with particular focus on how...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $807,330 on August 12, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Massachusetts General Hospital to develop potent antibody therapeutics against malaria parasites. The research, scheduled for completion by July 31, 2030, focuses on identifying and characterizing highly effective human monoclonal antibodies targeting the circumsporozoite...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $810,125 to the Regents of the University of California, San Francisco on June 9, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct a comprehensive research evaluation examining how perennial malaria chemoprevention (PMC) affects the development of naturally acquired immunity (NAI) to malaria in early childhood. The project leverages existing...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $202,055 Project Grant to Harvard T.H. Chan School of Public Health on August 13, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support research on Plasmodium falciparum apicomplexan amino acid transporter 2 (PfAPIAT2) and its proline transport capability. The research aims to characterize PfAPIAT2's role in proline transport across different...
- Federal Grant Award Summary Mercer University received a $230,463 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 3, 2026, with completion targeted for June 30, 2028. The research focuses on developing a novel multi-stage malaria vaccine antigen that targets multiple critical points in the Plasmodium parasite lifecycle. The project builds upon the institution's prior...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Maryland, Baltimore $445,488 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a two-year project period from July 1, 2025 through June 30, 2027. This Project Grant supports scientific research to characterize long non-coding RNAs (lncRNAs) in Plasmodium falciparum and elucidate their roles in gene regulation. The research deliverables include...
The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded a $436,750 Project Grant to the University of Georgia Research Foundation, Inc., effective July 3, 2026, with completion targeted for June 30, 2028. The research project, titled "Cellular and Molecular Profiling of Artemisinin-Induced Persister Phenotypes in P. Falciparum," will deliver cellular and molecular biology research outputs focused on understanding how the malaria parasite Plasmodium falciparum develops drug-resistant persister phenotypes in response to artemisinin antimalarial therapy. The funded research encompasses two primary research objectives: (1) development of chemical probes for gibberellin and fluridone to identify molecular interacting partners responsible for persister formation and dormancy recovery, supported by transcriptomic and metabolomic analysis and reverse genetics validation; and (2) creation and application of a novel high-content imaging assay to quantify persister formation rates, viability, and recovery timing. The deliverables will advance understanding of artemisinin resistance mechanisms in malaria parasites, with potential implications for improving treatment efficacy and supporting global malaria elimination efforts.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $436.8k | 7/7/26 |