Project Grant R21AI188314
- This federal Project Grant award of $422,814.00 was provided by the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research (CFDA 93.855) program. The project aims to develop and apply adversarial machine learning methods to predict the risk of animal viruses spilling over into humans, accounting for virus evolution. Key objectives include (i) predicting human-infection risk for viral sequence variants, (ii) characterizing and...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $220,096 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Michigan State University. The objective of this 2-year project, which runs from November 2024 to October 2026, is to elucidate the mechanisms of tetrodotoxin (TTX) biosynthesis in microbial symbionts. The researchers plan to leverage their discovery of TTX-producing bacteria on newt skin to sequence bacterial genomes,...
- This federal Project Grant award of $563,513.00 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855). The funding supports research at Arizona State University to investigate the patterning, growth, and maturation of the cortical microtubules in Toxoplasma, a unicellular parasite that causes diseases such as toxoplasmosis. The research aims to explore the initiation of patterning...
- This federal Project Grant award for $2,056,250.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to The Trustees of Columbia University in the City of New York, doing business as the Health Sciences Division. The grant, awarded on September 1, 2025, will fund a 5-year research project to develop novel computational tools and techniques leveraging machine learning, deep learning, and complex...
- The federal Project Grant award of $420,066.00 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) will fund research to systematically characterize how regulatory networks control secondary metabolism in microbes. The project aims to use genome-wide screens and multi-omics approaches to predict and access the unexplored biosynthetic potential of microbes, with the goal of accelerating the discovery,...
- This federal Project Grant award of $1,968,575.00 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), is focused on developing computational approaches and machine learning methods to predict DNA-binding specificities for transcription factor proteins and the functional effects of genetic variants within proteins. The overarching goal is to gain a predictive understanding of proteins, their interactions,...
- This $407,156 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports the development of chemical probes to explore the utility of recruiting the complement system for eliminating antibiotic-resistant bacterial pathogens. The research aims to generate multifunctional compounds that bind to the bacterium Pseudomonas aeruginosa and assess their ability to promote pathogen uptake...
- This federal Project Grant award of $3,055,197.00 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The objective of the project is to evaluate the potential impact of rapid detection of carbapenemase-producing organisms (CPOs) using a form-factor optimized phenotypic test paired with machine learning algorithms. The goal is to increase CPO detection, decrease time-to-identification of CPO...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under CFDA program 93.859 - Biomedical Research and Research Training, provides $333,076.00 to New York University (NYU) to develop novel statistical methods, algorithms, and pipelines for learning from complex, heterogeneous omics data. The project aims to innovate in studying subgroups within genomic, transcriptomic, or connectomics data, even amidst potential data shifts and multidimensional...
- This federal Project Grant award, valued at $622,130.00 and issued by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to investigate how bacterial pathogens manipulate atypical ubiquitin signaling pathways within host cells. The research aims to elucidate the molecular mechanisms by which specific bacterial effector proteins upregulate or downregulate Lys6-linked polyubiquitin signals,...
This federal Project Grant award, titled "PTSOMICS - MACHINE LEARNING-DRIVEN DISCOVERY AND ANALYSIS OF POLYMORPHIC TOXIN AND EFFECTOR SYSTEMS", was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855). The $416,625 award supports research to develop innovative machine learning approaches for identifying and characterizing novel bacterial protein toxins and effector systems, which play a critical role in host-pathogen interactions and bacterial disease pathogenesis. The project aims to expand the understanding of the organizational and evolutionary principles governing these complex molecular systems, leveraging advanced computational methods to unravel their intricate diversity and biochemical mechanisms. The award was granted on Aug 11, 2025 with an ultimate completion date of Jul 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $416.6k | 8/11/25 |