Project Grant R21AI186033
Award Date
1/14/25
Completion Date
12/31/26
Dollars Obligated
$244K
Federal Agency
National Institute of Allergy and Infectious Diseases
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
Bronx, NY 10461, USA
Similar Awards
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $244,440 to Albert Einstein College of Medicine to conduct research exploring the role of cytolytic ZEB2+ memory CD4+ T cells in providing protection against the liver stage of malaria infection. The goal is to gain insights into the cellular immune determinants associated with natural clinical immunity to malaria, which could inform...
This federal Project Grant award, totaling $820,246.00 and awarded on May 22, 2025 by the National Institute of Allergy and Infectious Diseases (CFDA 93.855 Allergy and Infectious Diseases Research), supports research to identify and characterize the secreted proteins from the Mycobacterium tuberculosis ESX5 transport system. The research aims to determine the role of these secreted proteins in tuberculosis (TB) disease pathogenesis and understand the immunological basis for why an ESX5 mutant...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Albert Einstein College of Medicine in Bronx, NY. The $1,486,800 award, with a project period from November 7, 2024 to October 31, 2029, supports research on the role of TNFRSF14 signaling in promoting antibody-dependent cell-mediated cytotoxicity (ADCC) as a potential strategy for herpes simplex virus (HSV) vaccine development. The...
This $252,280 federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will fund research to evaluate the role of monocyte cells in the development of an effective HIV vaccine response. The research project aims to investigate changes in monocyte gene expression following HIV infection, autoimmune disease, and vaccination, and to identify monocyte subtypes associated with antibody...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will provide $784,217 to the Research Foundation of the City University of New York (RFCUNY) - Lehman College to conduct research characterizing how cellular death signaling pathways contribute to both protective and injurious inflammation during bacterial infections. The research aims to identify novel signaling mechanisms...
This federal Project Grant award, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under CFDA 93.855 Allergy and Infectious Diseases Research, will support research to understand how caloric restriction can enhance immune memory and improve pathogen control. The $631,977 award to Weill Medical College of Cornell University aims to reveal the molecular mechanisms by which caloric restriction increases memory CD8+ T cell function and microbiome-derived acetate...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $558,501 to Albert Einstein College of Medicine to conduct research on the Crimean-Congo Hemorrhagic Fever Virus (CCHFV). The overarching goal is to address critical gaps in understanding the architecture, assembly, and functions of the CCHFV glycoprotein components and complexes, and their roles in virion...
This $125,160 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to characterize a novel bacterial immune system at The Ohio State University. The project aims to use cryogenic electron microscopy and biochemical/cellular assays to define the structure, assembly mechanisms, and functions of a two-component (A and B) complex involved in anti-phage defense. The research seeks to provide a...
This federal Project Grant award, totaling $472,210.00, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The purpose of the award is to investigate the spatiotemporal relationship between CD4+ T resident memory cells and neutrophil recruitment in the lungs during pneumonia, while developing a transcriptional atlas of immune processes in the experienced lung. Key objectives include...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $318,085.00 to conduct research on the role of cell, antigen, and antibody in controlling virus infection through Fc-dependent mechanisms. The key focus is on understanding how to optimize antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and...