Project Grant R01AI182043
Award Date
11/18/24
Completion Date
10/31/29
Dollars Obligated
$632K
Federal Agency
National Institute of Allergy and Infectious Diseases
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
New York, NY 10065, USA
Similar Awards
This $693,465 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports a research project to map the development of T cell immunity in lymph nodes from infancy to adulthood. The key objectives are to: 1) Determine how the spatial organization of T cells changes in the lymph node throughout childhood; 2) Examine how the lymph node shapes the CD8+ T cell response to infection in...
This $162,512 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to understand how pathogen exposure and inflammation impact the formation and function of long-lived effector CD8 T cells in the mature memory compartment. The grant recipient, the Regents of the University of Minnesota, will conduct experiments to identify the cytokines and other factors that promote...
The National Institute of Allergy and Infectious Diseases (NIAID) has awarded a $781,367 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Weill Medical College of Cornell University. The grant, awarded on January 25, 2024, will support research to define and maximize the impact of CD8+ T-cell selection on the landscape of HIV integration sites. The goal is to optimize strategies for eradicating the persistent reservoir of HIV-infected cells and achieve...
This federal Project Grant award, with an ID of DP2AI184830, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The $492,000 grant is funding research at the University of California, San Francisco (UCSF) to systematically investigate the mechanisms governing immunogenic cell death (ICD) - a critical process for launching effective immune responses against viral pathogens and tumors. The...
This federal Project Grant award, valued at $639,084 and issued by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to elucidate the heterogeneity of naïve CD8 T cells and its impact on immune responses and T cell homeostasis. The research will investigate both mouse and human naïve CD8 T cells, with the goal of developing strategies to induce protective naïve CD8 T cell immunity...
This $242,310 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to understand how the commensal microbiome is regulated and trafficked to the thymus during early life development. The research aims to elucidate the role of epithelial adherence and maternal IgG opsonization in shaping the microbiome-specific T cell repertoire. Key activities include quantifying...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $244,440 to Albert Einstein College of Medicine to conduct research on how inflammatory Ly6C+ monocytes respond to and help clear microbial pathogen infections. The research aims to define the chemotactic signals and mechanisms involved in how these monocytes home to infection sites, form stable clusters, and...
This federal Project Grant award of $107,948 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award supports research aimed at engineering B cells to secrete broadly neutralizing antibodies that could help control HIV in people living with the virus. The key objectives are to: 1) design synthetic protein signaling molecules to enhance B cell function, 2) test the ability of these...
This federal Project Grant award in the amount of $704,041 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award supports research on sex-dependent innate immune mechanisms related to type 2 immunity, obesity, and parasitic helminth infections. The project aims to investigate sex differences in macrophage and eosinophil function, determine how the protein RELM-α promotes macrophage...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research (CFDA 93.855) program, provides $451,292 to The Regents of the University of California, doing business as the University of California, Berkeley (UC Berkeley), over a 5-year period from Sep 1, 2024 to Aug 31, 2029. The award aims to uncover neuronal mechanisms orchestrating metabolic adaptations to bacterial infections, specifically...