This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $451,000.00 to The University of Texas Southwestern Medical Center to develop an "Alveolus on a Chip Model of Non-Tuberculous Mycobacteria Infection". The project aims to leverage a human lung-on-a-chip model to gain insights into the pathogenesis of non-tuberculous mycobacteria (NTM) infections and identify potential therapeutic targets. The research will investigate the transcriptional response of airway cells to NTM infection, the role of innate immune mechanisms in controlling NTM infection, and the impact of NTM infection on recruiting myeloid cells from the vasculature. This 2-year project runs from July 1, 2025 to June 30, 2027 and is expected to provide a better understanding of NTM infections, which have emerged as a significant public health concern.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $451.0k | 6/27/25 |