This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $239,348 to investigate the role of regulatory T cells (Tregs) in protecting against Pseudomonas aeruginosa lung infections. The award, granted to The Trustees of Columbia University in the City of New York, Health Sciences Division, will evaluate how Tregs alter the airway metabolome to limit bacterial growth and biofilm formation, as well as assess the contribution of Treg-derived adenosine signaling through CD73 expression. The findings are expected to reveal new pathways for controlling intractable P. aeruginosa lung disease. This award, with a performance period from November 2024 to October 2026, supports fundamental research to advance the understanding of host immune responses and their impact on bacterial pathogenesis.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $239.3k | 11/12/24 |