Project Grant R21AG101626
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded $484,392 to Brigham and Women's Hospital Inc. on September 10, 2025, under the Aging Research program (CFDA 93.866) to support a career development project directed by Dr. Lisa Simon, MD DMD. This Paul B. Beeson Emerging Leaders Career Development Award funds research evaluating the effect of a new Medicare dental benefit on health outcomes for older adults. The project leverages a 2023 Medicare policy change that expanded...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded $540,629 to the University of Massachusetts Lowell on August 15, 2025, under the Oral Diseases and Disorders Research program (CFDA 93.121) to support research investigating human oral host-pathogen interactions and dysbiosis modulation. The project, scheduled for completion by August 14, 2027, focuses on developing and validating an immunocompetent three-dimensional (3D) in vitro model...
- Federal Grant Award Summary Augusta University Research Institute, Inc. received a $770,578 Project Grant award dated August 22, 2025, from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121). The award supports research investigating senescent periodontal ligament cells as a therapeutic target for age-associated periodontitis, with an ultimate completion date of May 31, 2030. The research addresses the...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded University of Massachusetts Lowell $100,676 under the Oral Diseases and Disorders Research program (CFDA 93.121) to develop a three-dimensional (3D) in vitro human periodontal sulcus tissue model for studying early indicators of oral dysbiosis. The research deliverable consists of an advanced tissue culture system that replicates the anatomical complexity, polymicrobial conditions,...
- Federal Grant Award Summary The University of Florida received a $639,248 Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), awarded June 1, 2025, with completion scheduled for May 31, 2027. This award supports statistical methodology development and secondary analysis of the National Health and Nutrition Examination Survey (NHANES) to assess person-level marginal associations between...
- Federal Grant Award Summary Mayo Clinic received a $332,787 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), effective August 14, 2025, with a completion date of August 13, 2027. This research initiative investigates the association between oral microbiota composition and both biomarkers of Alzheimer's Disease and Related Dementias (ADRD) pathophysiology and mid-life cognitive...
- Federal Grant Award Summary Award Details: The National Institute of Dental and Craniofacial Research (NIDCR) awarded Augusta University Research Institute, Inc. a Project Grant totaling $645,009 under the Oral Diseases and Disorders Research program (CFDA 93.121). The award period runs from June 15, 2025, through June 14, 2027. Research Scope: This grant funds a research project investigating the molecular mechanisms of alveolar bone loss in periodontitis through examination of...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded the University of Florida a $307,000 Project Grant effective July 15, 2025, through July 14, 2027, under the Oral Diseases and Disorders Research program (CFDA 93.121). This research initiative investigates the expression of cellular senescence markers in gingival tissue biopsies to elucidate the mechanisms by which Type 2 diabetes mellitus (T2DM) contributes to periodontal disease...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded the University of Pittsburgh $311,687 on June 10, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to support a two-year research project concluding June 9, 2028. The award funds basic research investigating the mechanisms of age-related inflammatory dysregulation in periodontal disease pathogenesis, with a specific focus on the role of Triggering Receptor...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded MD Anderson Cancer Center a $1,470,872 Project Grant on March 1, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121) to support a five-year research initiative through February 28, 2031. This award funds research titled "Elucidating Subclonal Evolution and Fitness Dynamics in Oral Carcinogenesis," which aims to improve risk stratification and early detection...
The National Institute on Aging awarded a $460,625 Project Grant (CFDA 93.866 – Aging Research) to the University of Massachusetts Medical School on July 15, 2026, for a 24-month research initiative examining oral health outcomes in U.S. nursing homes. Under this R21 exploratory grant, the research team will leverage the federally mandated Minimum Data Set 3.0 (MDS) collected on virtually all nursing home residents to establish contemporary national estimates of oral health indicators in this vulnerable population. The project will merge MDS data (2011–2023) with Medicare claims information, nursing home operational records, and area-level workforce data to identify populations with the greatest unmet oral health needs and evaluate the effectiveness of regulatory and policy strategies in improving oral health care delivery within nursing facilities. This research directly supports the National Institute of Dental and Craniofacial Research (NIDCR) Strategic Goal 3 and responds to longstanding recommendations in the 2000 Surgeon General Oral Health Report and the 2021 NIDCR Oral Health Report calling for improved oral health monitoring and care in nursing homes. The project addresses a critical data gap: nursing home residents have been systematically excluded from national oral health surveillance despite representing a frail, elderly population with documented high burden of untreated dental disease, tooth loss, and periodontitis. By establishing baseline measurements and predictive models using existing administrative data infrastructure, the initiative will generate essential evidence for program planning, policy evaluation, and resource allocation to address oral health disparities in long-term care settings.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $460.6k | 7/2/26 |