Project Grant R21AG093384
- This Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) is providing $628,753 to SRI International to conduct research on the thermoregulatory physiology of menopausal hot flashes. The goal is to determine if precisely timed and targeted localized peripheral cooling can mitigate menopausal hot flashes. The research will combine a novel hot flash detection algorithm developed by SRI with a novel cooling approach to help alleviate this...
- The University of Arizona received a $466,470 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), to investigate the impact of phthalate exposures on female reproduction and metabolism. The project aims to test the hypothesis that phthalate mixture exposure leads to stimulated fatty acid synthesis with concurrent inhibition of fatty acid oxidation, which may underlie the associations between...
- The National Institute of Environmental Health Sciences (NIEHS) awarded a $2,737,859 Project Grant (CFDA 93.113, Environmental Health) to the University of Illinois to conduct research on the "Impacts of Phthalate Exposure on the Development of Social Behavior Circuits". The 4-year award, running from September 2025 to September 2029, aims to investigate how exposure to phthalates, a class of endocrine-disrupting chemicals, during development can lead to alterations in brain...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), which is part of the Environmental Health federal grant program (CFDA 93.113), provides $452,945.00 to the University of Illinois to conduct research on the modulation of the ovarian lipidome by environmental exposures. The key objectives of the research project are to: 1) develop a spatial map of the human and mouse ovarian lipidome using mass spectrometry imaging techniques, and 2) investigate how...
- This Project Grant award of $432,250.00 was issued on September 15, 2025 by the Department of Health and Human Services' National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310). The award was provided to Beth Israel Deaconess Medical Center, Inc. (Bidmc) in Massachusetts to conduct research on the role of orexin neuropeptides in regulating sleep disturbances, anxiety, and hot flashes experienced by women during the menopausal transition. The project aims to...
- This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113) provides $521,992 in funding to Midwestern University to investigate how exposure to phthalates during critical developmental windows can disrupt spermatogenesis through the disruption of LRH1 signaling in Sertoli cells. The two-year project, running from September 1, 2025 to August 31, 2028, aims to elucidate the molecular...
- The University of Illinois was awarded a $108,512 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113). The grant, titled "LIPID-BASED INTERVENTIONS TO MITIGATE THE IMPACT OF ARSENIC ON MICROGLIAL FUNCTION AND NEUROBEHAVIOR", will fund research to investigate how the essential fatty acid docosahexaenoic acid (DHA) can protect against the neurobehavioral impacts of arsenic exposure. The...
- This $150,000 Project Grant was awarded on September 1, 2025 by the Department of Health and Human Services National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310). The grant will fund the "Waning Moon" intervention, a culturally tailored health education program designed to address menopause symptoms and cardiovascular disease risk in urban American Indian/Alaska Native women. The program will provide education on conventional and complementary...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), will provide $719,892 to New York University to conduct research on the relationship between infant exposure to phthalates and bisphenols and reproductive development during the "minipuberty" period in the first six months of life. The project will enroll 480 infants in the ongoing NYU Children's Health and Environment...
- The University of Illinois was awarded a $626,812 Project Grant from the National Institutes of Health's National Institute of Environmental Health Sciences (CFDA 93.113 Environmental Health) to study cytoplasmic remodeling during the vertebrate oocyte-to-embryo transition. This 5-year research project aims to determine the role of endoplasmic reticulum (ER) remodeling, mRNA-ER association, and RNA phase transition as novel mechanisms underlying this critical reproductive process. The research...
The University of Illinois was awarded a $445,719 Project Grant from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) on September 15, 2025. The funding supports research to investigate the association between phthalate exposure and hot flashes in aging women, as well as the underlying mechanism of oxidative stress. The research aims to examine whether a cumulative mixture of phthalates is associated with an increased risk of hot flashes in midlife women, and whether oxidative stress mediates this relationship. The project will be conducted over a period of approximately 2 years, with an ultimate completion date of August 31, 2027. The award reflects the NIH's interest in advancing scientific understanding of the risk factors and mechanisms underlying the common menopausal symptom of hot flashes, which negatively impacts quality of life for millions of women in the U.S.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $445.7k | 9/12/25 |