Project Grant R21AG093284
- The National Institute on Aging (NIA), within the U.S. Department of Health and Human Services, has awarded a $277,391 Project Grant under the Aging Research federal grant program (CFDA 93.866) to Amira Health Inc. of Massachusetts. The purpose of this Phase I Small Business Innovation Research (SBIR) award is to validate the effectiveness of Amira's "Terra" device, a closed-loop temperature control system designed to mitigate vasomotor symptoms (hot flashes) and improve sleep...
- The University of Illinois was awarded a $445,719 Project Grant from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) on September 15, 2025. The funding supports research to investigate the association between phthalate exposure and hot flashes in aging women, as well as the underlying mechanism of oxidative stress. The research aims to examine whether a cumulative mixture of phthalates is associated with an increased risk of hot flashes in midlife...
- The National Science Foundation awarded a $255,742 Project Grant to Lisa Health Inc. on May 15, 2021 for research toward developing the first novel multi-sensor smart wearable system for hot flash detection under the Engineering federal grant program (CFDA 47.041). Lisa Health will conduct research and development of a wearable device and associated software application utilizing multiple sensors to detect hot flashes and collect related physiological data. The project aims to provide an...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $788,301 Project Grant under the Cardiovascular Diseases Research (CFDA 93.837) federal grant program to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH). The grant supports a 5-year research project to study the relationship between menopause-related vasomotor symptoms (hot flashes) and cardiovascular disease (CVD) risk among peri- and post-menopausal women with cardiometabolic risk...
- This Project Grant award of $432,250.00 was issued on September 15, 2025 by the Department of Health and Human Services' National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310). The award was provided to Beth Israel Deaconess Medical Center, Inc. (Bidmc) in Massachusetts to conduct research on the role of orexin neuropeptides in regulating sleep disturbances, anxiety, and hot flashes experienced by women during the menopausal transition. The project aims to...
- This $275,765 Project Grant awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program aims to develop and test prototypes of personal active cooling garments to protect at-risk patients from extreme heat waves. The grant is awarded to General Engineering & Research, L.L.C., a for-profit, economically disadvantaged woman-owned small business located in San Diego, California. The project will leverage the...
- This $150,000 Project Grant was awarded on September 1, 2025 by the Department of Health and Human Services National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310). The grant will fund the "Waning Moon" intervention, a culturally tailored health education program designed to address menopause symptoms and cardiovascular disease risk in urban American Indian/Alaska Native women. The program will provide education on conventional and complementary...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports the development of the "MI-HELPER" device, a novel thermodynamic neuromodulation approach for migraine relief. The $983,042 award to Cooltech, LLC aims to demonstrate the device's capacity for fast, convenient, and drug-free symptom reduction for migraine through the targeted...
- This $399,813 Project Grant award from the National Institute on Aging (NIA), under the Aging Research grant program (CFDA 93.866), supports the development of WHIM (Women's Health in Menopause), a digital health product designed to improve the menopause-related experience for midlife women. The project extends an existing digital behavioral intervention platform, GEMINI, to create WHIM, which will incorporate the MENOGAP patient education program and enhance the platform with additional...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $298,883 to Iaterion, Inc. to develop a safer menopausal hormone therapy (MHT) formula that can be used long-term to treat protracted menopausal symptoms and prevent chronic diseases like osteoporosis, diabetes, obesity, and metabolic syndrome. The project aims to create an estradiol/reprogramming ligand combination that can potentially replace the progestin component of current MHT...
This Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) is providing $628,753 to SRI International to conduct research on the thermoregulatory physiology of menopausal hot flashes. The goal is to determine if precisely timed and targeted localized peripheral cooling can mitigate menopausal hot flashes. The research will combine a novel hot flash detection algorithm developed by SRI with a novel cooling approach to help alleviate this disruptive condition that affects many women. The 30-month project will monitor 30 participants with menopausal hot flashes to assess relevant physiological signals and the impact of the cooling intervention. This work aims to advance the understanding of hot flash thermoregulatory mechanisms and explore new treatment options, aligning with the Trans-NIH Strategic Plan for Women's Health Research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $628.8k | 9/16/25 |