Project Grant R21AA032098
- The National Institute on Alcohol Abuse and Alcoholism awarded the Board of Regents of the University of Nebraska, through its University of Nebraska Medical Center division, $219,118 on August 1, 2026, under the Alcohol Research Programs (CFDA 93.273). The award funds research into the molecular mechanisms linking chronic alcohol consumption to prostate cancer progression and metastatic castration-resistant prostate cancer. The recipient will investigate alcohol-induced endoplasmic reticulum...
- The National Institute on Alcohol Abuse and Alcoholism awarded the Board of Regents of the University of Nebraska, acting through its University of Nebraska Medical Center division, $194,292 on June 11, 2026, under the Alcohol Research Programs (CFDA 93.273) to support a five-year research and career development project investigating epigenetic mechanisms in fetal alcohol spectrum disorder. The award funds a research program designed to identify ethanol-induced epigenetic alterations responsible...
- The National Institute on Alcohol Abuse and Alcoholism awarded the Board of Regents of the University of Nebraska $368,551 on May 4, 2026, under the Alcohol Research Programs (CFDA 93.273) to support research on novel targeting mechanisms for alcohol-enhanced colorectal liver metastasis. The recipient, through its University of Nebraska Medical Center division in Omaha, Nebraska, will develop and optimize nanoparticle formulations to inhibit hepatic macrophage activation and hepatic stellate...
- The National Institute on Alcohol Abuse and Alcoholism awarded Weill Medical College of Cornell University $591,468 on September 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to conduct longitudinal neuroimaging analysis identifying neural risk factors for drinking onset in young adulthood. The recipient will apply machine learning analysis to nine years of longitudinal neuroimaging, behavioral, and neuropsychological data from 466 adolescents (baseline ages 12–18 years) enrolled in...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Medical University of South Carolina $488,077 on September 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate molecular and functional adaptations in the nucleus reuniens, a midline thalamic region implicated in alcohol-related cognitive deficits. The research addresses how chronic alcohol exposure produces cognitive dysfunction that impairs treatment outcomes and increases relapse risk. The project will...
- The National Institute on Alcohol Abuse and Alcoholism, part of the Department of Health and Human Services National Institutes of Health, awarded $702,720 to Indiana University Indianapolis on August 10, 2026, under the Alcohol Research Programs (CFDA 93.273) project grant R01AA031671. The award funds research investigating posterior default mode network modulation as a treatment target in alcohol use disorder. The research examines how dysfunction in the medial posterior default mode...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of New Mexico Health Sciences Center $160,744 on March 9, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate electrophysiological mechanisms of prenatal alcohol exposure (PAE) effects on cognitive control. The project combines translational touchscreen testing and in vivo electrophysiology to determine how PAE impairs executive function domains in mouse models. The research hypothesizes that...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Medical College of Wisconsin, Inc., $248,959 on September 12, 2025, under the Alcohol Research Programs (CFDA 93.273) to conduct a five-year longitudinal study examining reciprocal associations between brain function and alcohol use trajectories in adolescents and young adults. The recipient will assess prospective long-term associations between reward processing, cognitive control, and alcohol use patterns using two large...
- The National Institute on Alcohol Abuse and Alcoholism awarded Auburn University $629,828 on September 20, 2025, under the Alcohol Research Programs (CFDA 93.273) to conduct a multimodal assessment of neural, neuroendocrine, and immune responses to alcohol cues in binge drinkers across laboratory and real-world settings through August 31, 2030. The research examines neurobiological factors—neural activation, cortisol dysregulation, interleukin-6 elevation, and craving responses—as components...
- The National Institute on Alcohol Abuse and Alcoholism awarded Northwestern University $100,228 on December 18, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate projection-specific endocannabinoid signaling mechanisms in ethanol-related behaviors. The research examines how ethanol affects endocannabinoid-cannabinoid receptor type 1 signaling at dorsolateral striatum terminals in the external segment of the globus pallidus, and how altered signaling at these terminals...
The National Institute on Alcohol Abuse and Alcoholism awarded the Board of Regents of the University of Nebraska, through its University of Nebraska Medical Center division, $402,938 on August 3, 2026, under the Alcohol Research Programs grant (CFDA 93.273). The award funds development of an automatic segmentation algorithm using deep learning to identify and measure the bed nucleus of the stria terminalis (BNST) in brain imaging data. The research applies this algorithm to the NCANDA dataset to investigate BNST development during adolescence and its relationship to the emergence of anxiety, depression, and alcohol consumption. Aim 1 develops the automated BNST segmentation model via deep learning, addressing challenges of limited annotated training samples and inconsistency in segmentation outputs across data sources. The approach includes generating synthetic brain-segmented BNST image pairs using a generative adversarial network and transfer learning for data augmentation. The funding period runs from August 3, 2026, to July 31, 2028. Work is performed in Nebraska.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $402.9k | 8/6/26 |