Project Grant R01AA032306
- The National Institute on Alcohol Abuse and Alcoholism awarded The Medical College of Wisconsin, Inc., $248,959 on September 12, 2025, under the Alcohol Research Programs (CFDA 93.273) to conduct a five-year longitudinal study examining reciprocal associations between brain function and alcohol use trajectories in adolescents and young adults. The recipient will assess prospective long-term associations between reward processing, cognitive control, and alcohol use patterns using two large...
- The National Institute on Alcohol Abuse and Alcoholism awarded the Board of Regents of the University of Nebraska, through its University of Nebraska Medical Center division, $402,938 on August 3, 2026, under the Alcohol Research Programs grant (CFDA 93.273). The award funds development of an automatic segmentation algorithm using deep learning to identify and measure the bed nucleus of the stria terminalis (BNST) in brain imaging data. The research applies this algorithm to the NCANDA dataset...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Research Foundation for the State University of New York $2.12 million on August 4, 2026, under the Alcohol Research Programs (CFDA 93.273) to support research into neurobiological factors contributing to tolerance to the adverse consequences of alcohol. The research examines how individuals vary in their sensitivity to the aversive effects of alcohol and how tolerance to these effects develops following repeated alcohol...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Medical University of South Carolina $488,077 on September 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate molecular and functional adaptations in the nucleus reuniens, a midline thalamic region implicated in alcohol-related cognitive deficits. The research addresses how chronic alcohol exposure produces cognitive dysfunction that impairs treatment outcomes and increases relapse risk. The project will...
- The National Institute on Alcohol Abuse and Alcoholism awarded Yale University $713,580 on August 6, 2026, under the Alcohol Research Programs (CFDA 93.273) to conduct imaging research on sex differences in the cortical reward system of people with alcohol use disorder. The research examines dopamine neurotransmission in the mesocortical pathway—which regulates executive functions, reward sensitivity, stress response, and cognitive function—comparing men and women with alcohol use disorder....
- The National Institute on Alcohol Abuse and Alcoholism awarded Icahn School of Medicine at Mount Sinai $3.112 million on August 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate histone acetylation and synaptic mechanisms underlying resilience to compulsive-like alcohol drinking. The recipient will conduct research on the role of SIRT7, a histone deacetylase, in D1-type medium spiny neurons within the dorsomedial striatum, examining how epigenetic changes and synaptic...
- The National Institute on Alcohol Abuse and Alcoholism awarded New York University $746,805 on September 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate developmental pathways linking prenatal alcohol exposure to adult externalizing outcomes in adolescents. The research, titled the DREAMS study (Developmental Research on Externalizing Outcomes Among Youth with Prenatal Alcohol Exposure: Mediating Role of Cognitive Control and Sleep), leverages the NIH SAFE PASSAGE and...
- The National Institute on Alcohol Abuse and Alcoholism awarded Children's Research Institute $648,180 on June 20, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate mechanisms and potential pharmacotherapy of neurocognitive deficits in fetal alcohol spectrum disorders. The research examines the long-term neurobehavioral impact of prenatal alcohol exposure, with focus on apolipoprotein E (APOE) signaling in the motor cortex as a therapeutic target. The project builds on...
- The National Institute on Alcohol Abuse and Alcoholism awarded Auburn University $629,828 on September 20, 2025, under the Alcohol Research Programs (CFDA 93.273) to conduct a multimodal assessment of neural, neuroendocrine, and immune responses to alcohol cues in binge drinkers across laboratory and real-world settings through August 31, 2030. The research examines neurobiological factors—neural activation, cortisol dysregulation, interleukin-6 elevation, and craving responses—as components...
- The National Institute on Alcohol Abuse and Alcoholism awarded New York University School of Medicine $2.920164 million on August 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to develop and evaluate a precision prevention approach for identifying and addressing behavioral health treatment gaps that drive suicide risk. The project will identify subgroups at highest risk of suicidal thoughts and behaviors, characterize which combinations of mental and substance use disorders place...
The National Institute on Alcohol Abuse and Alcoholism awarded Weill Medical College of Cornell University $591,468 on September 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to conduct longitudinal neuroimaging analysis identifying neural risk factors for drinking onset in young adulthood. The recipient will apply machine learning analysis to nine years of longitudinal neuroimaging, behavioral, and neuropsychological data from 466 adolescents (baseline ages 12–18 years) enrolled in the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA). The research tests the hypothesis that multiple subtypes of neurodevelopmental imbalance across reward, emotion, and executive control domains predict heavy drinking in young adulthood, stratified by sociodemographic factors and life experiences. The work will develop a self-supervised longitudinal correlation analysis method to identify heterogeneous neural pathways to drinking onset, with the goal of directing preventive interventions that reduce alcohol use disorder risk in later life. Performance occurs in New York, New York. The period of performance runs from September 1, 2026, through June 30, 2031. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $591.5k | 8/13/26 |