Project Grant R18NS145979
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $1,042,170 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective September 1, 2025 through August 31, 2033. The award supports computational neuroscience research focused on model-based analysis of brain stimulation and recording...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $262,089 to Lawrence Berkeley National Laboratory on September 15, 2025, under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) to enhance the AQNWB (Advancing Quantitative Neurophysiology with NWB) platform. AQNWB is an open-source C/C++ application programming interface (API) designed to enable direct data...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Boston University a $465,500 Project Grant on July 5, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop advanced neuromodulation technology. The award supports research and development of a Close-Loop Deep Brain Optoacoustic Stimulation (DBOAS) system designed to overcome limitations of existing electrical deep...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke awarded $336,935 to the University of California, Los Angeles under the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) on August 1, 2025, for a project period extending through July 31, 2027. The primary deliverable is the development and technical refinement of dual in vivo whole-cell and large-scale extracellular Neuropixels recording techniques in awake...
- Federal Grant Award Summary Great Lakes Neurotechnologies Inc. received a $1,134,607 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded August 21, 2025, with a completion date of June 30, 2027. The award funds development of DBS-EXPERT PRO, a commercially viable expert system designed to optimize postoperative Deep Brain Stimulation (DBS)...
- Federal Project Grant Summary Massachusetts Institute of Technology received a $2.72 million Project Grant from the National Institute of Neurological Disorders and Stroke under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) for the period August 1, 2025 through July 31, 2028. The project focuses on developing high-speed complementary metal-oxide-semiconductor (CMOS) image sensors with pixel-wise programmable...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Massachusetts Institute of Technology (MIT) a Project Grant totaling $1,045,760 (awarded August 1, 2025, with completion by July 31, 2028) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports a comprehensive culture change initiative within MIT's Brain and Cognitive Sciences Department to advance research rigor...
- Federal Project Grant Award Summary Dartmouth College's Office of Sponsored Projects received a $484,125 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective July 1, 2025, through June 30, 2030. The award funds research investigating mitochondrial dynamics underlying oligodendrocyte generation—specifically how changes in mitochondrial...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a $616,585 Project Grant effective May 1, 2026 through April 30, 2031, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This award funds the development of tools and methodologies to enable brain-wide chronic electrophysiology recording in freely moving rodents using next-generation Neuropixels...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $448,200 under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) to the Research Foundation of The City University of New York, effective September 30, 2025 through September 29, 2028. This project grant supports fundamental research to elucidate the mechanisms regulating neuron cell number and dendrite arbor...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded Dartmouth College $1,010,880 under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) to translate novel carbon coating technology into integrated neurotransmitter sensors for clinical application. The award, which commenced May 1, 2026 and extends through April 30, 2029, supports a collaborative effort among Dartmouth College, VA Medical Center, Beth Israel Deaconess Medical Center (neurosurgery), and industry partner NeuroOne to develop and validate an advanced neurochemical sensing platform. The project builds upon recent discoveries demonstrating that mild annealing dramatically improves the electrochemical stability of electroplated carbon coatings, enabling conventional microelectrodes to function as high-performance sensors capable of fast-scan cyclic voltammetry (FSCV)-based neuromodulator sensing. The primary deliverable is the development of a prototype integrated probe combining electrical recording and FSCV capabilities for simultaneous detection of neural activity and neurotransmitters such as dopamine with sub-second temporal resolution. The research team will optimize this technology for integration into NeuroOne's FDA-cleared stereoelectroencephalography (SEEG) electrode platform to advance toward first-in-human clinical studies. The project aims to establish the foundational clinical-facing potentiostat design, software infrastructure, and regulatory pathway necessary to shift neurophysiological monitoring from electrophysiology-only approaches to combined electrophysiology and chemical sensing modalities, ultimately providing clinicians and researchers with enhanced diagnostic and monitoring capabilities for brain disorders and conditions.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.0m | 5/4/26 |