This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, will support the development of a closed-loop deep brain stimulation (DBS) computational framework. The $146,500 award, effective from July 2, 2024 to June 30, 2028, aims to create novel open-loop and closed-loop multi-input multi-output (MIMO) DBS techniques to provide...
This federal Project Grant award of $657,958, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to elucidate the cellular and network mechanisms underlying epileptic activity and seizures, as well as investigate the neuronal impact of neurostimulation for treating drug-resistant epilepsy. The 5-year award to Trustees of Boston University...
This Project Grant award of $548,088.00 was made on December 1, 2024 by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research by Trustees of Boston University to understand the role of local and long-range cortical circuits in tactile perception and sensory processing. Key activities include: Obtaining a fine-scale wiring diagram of the primary...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is funding research to establish the causal roles of the dorsolateral prefrontal cortex (DLPFC) and dorsal premotor cortex (PMd) in perceptual decision-making behavior. The $436,850 award to Trustees of Boston University, doing business as Boston University Medical Campus, will be...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $469,500 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Michigan Technological University. The grant, titled "Dissecting Neural Circuit Mechanisms Underlying Pallidal Deep Brain Stimulation," will fund research to identify the neural elements and circuits necessary for the therapeutic effects of deep brain stimulation (DBS) of the globus...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $2,359,174 Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to conduct research on the biophysical mechanisms of cortical microstimulation. The project aims to develop a more mechanistic understanding of how direct local electrical stimulation...
This $1,836,842 Project Grant from the National Institute of Neurological Disorders and Stroke will support research into sensory-motor strategies for odor-guided navigation. Funded under the Extramural Research Programs in the Neurosciences and Neurological Disorders program, the Trustees of Boston University will conduct research to better understand how spatial information is encoded in the olfactory bulb during odor-guided search behaviors in mice. Researchers will use new imaging tools to...
This Project Grant award of $527,037 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award supports research at New York University (NYU) to investigate how the basal ganglia and motor thalamus in the human brain integrate cognitive and motor processes, with the goal of developing brain stimulation strategies to treat movement and...
This Cooperative Agreement award, totaling $1,419,954.00, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) grant program. The award aims to advance adaptive deep brain stimulation (aDBS) therapy for Parkinson's disease through the following key objectives: Reduce the complexity and risk of chronic cortical sensing by placing leads in the subgaleal space rather...
This Project Grant award of $749,227 from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) to Trustees of Boston University will fund the acquisition of a state-of-the-art three-photon microscopy system with fluorescence and phosphorescence imaging capabilities. This multi-user facility at Boston University's Neurophotonics Center will enable NIH-funded investigators to study deep brain structure and function in vivo, advancing research on normal...