Project Grant R01NS142455
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a Project Grant of $147,486 on June 16, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to support research on quantifying the spatial stability of sensory stimulation projected fields for sensory neuroprostheses. The research deliverables include the development of a quantitative framework and...
- Federal Project Grant Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a $409,139 Project Grant on August 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the computational, behavioral, and neural mechanisms underlying state-driven active sensing. The research will span five years through June 30, 2030, and will examine how animals switch between...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a Project Grant of $580,924 (awarded April 17, 2026; completion March 31, 2031) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to develop and optimize ionic direct current (IDC) stimulation as a novel neuromodulation technology. The research deliverables include computational models predicting the effects of IDC...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a Project Grant (R21) totaling $232,938 on February 17, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports research investigating neuronal membrane proteasome-derived peptide (NMP-peptide) signaling in the peripheral nervous system, with performance scheduled through January 31,...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a Project Grant totaling $120,987 on August 4, 2025, to support research under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853). The research, which extends through July 31, 2027, investigates the molecular mechanisms underlying interstitial axon branching in the mammalian cerebral cortex. The study employs novel...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a Project Grant of $773,607 on August 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to support a two-year research initiative concluding July 31, 2027. This award funds the development of brain-penetrant, histone-evicting anthracycline drugs targeting diffuse midline glioma (DMG), a...
- Federal Cooperative Agreement Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a $1,033,079 Cooperative Agreement on May 8, 2025, under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) to expand training and support services for next-generation electrophysiology probe users. The award will fund at least four training classes annually through April 30, 2030,...
- Federal Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded The Johns Hopkins University a $682,299 Project Grant effective August 1, 2025, through July 31, 2029, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The research project, titled "Ultrafast Optical Brain Imaging via Blurred Matrix Completion," focuses on developing an advanced computational imaging approach...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a $155,000 project grant effective July 8, 2025 through June 30, 2027 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853). The award supports the characterization of an aminoacyl-tRNA synthetase complex interacting multifunctional protein-2 (AIMP2) variant-linked mouse model of Parkinson's disease. The...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a Project Grant totaling $214,101 on March 6, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds a mentored surgeon-scientist career development initiative (K08 mechanism) focused on advancing glioblastoma treatment through innovative drug delivery technologies. The primary research...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a $616,585 Project Grant effective May 1, 2026 through April 30, 2031, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This award funds the development of tools and methodologies to enable brain-wide chronic electrophysiology recording in freely moving rodents using next-generation Neuropixels 2.0 probes. The project will deliver three primary products: robot-assisted surgical tools for multi-probe implantation in mice and rats, anatomically-based targeting and probe trajectory planning software, and optimized data acquisition and processing systems capable of handling high-volume electrophysiological data streams (1.3-4.0 terabytes per hour). These tools will be made freely available to the neuroscience research community and will be benchmarked against a challenging scientific application involving brain-wide spiking activity and local field potential recordings during complex freely moving rodent navigation tasks. The project aims to significantly reduce multi-probe implantation surgical time from the current 14-18 hour standard to approximately eight hours with reduced surgical risk and improved reliability, thereby enabling broader adoption of advanced brain-wide electrophysiology techniques across the research community. Building upon previously developed technology including the SpikeGLX data acquisition platform and a Neuropixels NXT probe developed with prior NIH U01 support, this award will advance the technical capabilities required for simultaneous multi-probe neural recordings in behaving animals.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $616.6k | 5/1/26 |