The University of New Mexico received a $430,251 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) to conduct genetic mapping research on advanced intercross lines of the Biomphalaria glabrata snail, a vector for the schistosomiasis parasite. The research aims to identify genomic regions and genes that regulate schistosome resistance and per capita cercarial production in these snails, with the goal of...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $103,256 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Medical College of Wisconsin, Inc. The grant, entitled "Effects of a Chromosomal Inversion on Gene Regulation in a Major Malaria Vector", aims to study the mechanisms by which a chromosomal inversion in Anopheles coluzzii mosquitoes confers resistance to malaria infection. The research will biochemically and...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $479,730 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Wisconsin - Madison. The 5-year grant, effective from December 1, 2024 to November 30, 2029, will support research to elucidate the mechanisms by which prophages (viral DNA) in the gut symbiont Limosilactobacilus reuteri modulate the production of the antimicrobial compound reuterin. The research aims to...
This federal Project Grant award of $429,000.00, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to examine chromatin architecture and gene regulatory networks in Anopheles coluzzii mosquito hemocyte cells. The key objectives are to 1) map chromatin architecture during immune activation in mosquito hemocyte cells, and 2) identify gene regulatory networks for the immune...
The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), awarded a $560,178 Project Grant to the University of Wisconsin - Madison. The goal of this 5-year grant, which runs from Jul 25, 2025 to Jun 30, 2030, is to understand the dynamics of the interaction between Staphylococcus aureus bacteriophages, the bacteria, and the mammalian host. Specifically, the research aims to elucidate the...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $402,731 Project Grant under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855) to the University of Washington. The objective of this R38 grant is to increase the number of next generation physician-scientists who can apply knowledge of microbiology, immunology, and research techniques to improve reproductive, maternal, and child health. The grant will support 4 physician-scientists in...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $390,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Regents of the University of Idaho. The grant will fund research to better understand the developmental cycle of chlamydial bacteria, which cause various infectious diseases in humans. Specifically, the project aims to develop a CRISPR-based knockdown screen to assess the role of essential genes in regulating chlamydial...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $303,076 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Washington. The grant, awarded on November 5, 2024, supports research to understand how viruses evade and co-opt the body's innate immune defenses, specifically focusing on how enteric viruses develop resistance to antimicrobial peptides called defensins. The research aims to elucidate the molecular,...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $769,414 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The University of Iowa. The grant, awarded on July 9, 2025, will support research investigating how the cellular protein SAMHD1 regulates innate immune responses and HIV-1 gene expression in macrophages. The research aims to define the mechanisms by which SAMHD1 suppresses type I interferon induction and NF-kB activation...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $206,116 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Oregon Health & Science University (OHSU) to develop novel 4-aminoquinoline compounds as therapeutics against multi-drug resistant Plasmodium falciparum, the deadliest species of malaria parasite. The project aims to further develop a compound, MH02-060, that has shown enhanced metabolic stability and in vivo efficacy...