Project Grant R15AG078906

Award Date 9/1/22
Completion Date 8/31/25
Dollars Obligated $828K
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Memphis, TN 38152, USA
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This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) supports a comprehensive study on the role of mitochondrial function in aging-related diseases. The $2,010,291 award to The Johns Hopkins University will leverage genetic data, metabolomics, and proteomics from over 680,000 participants to identify novel biomarkers and causal relationships between mitochondrial dysfunction and conditions like all-cause mortality, cardiovascular disease, and frailty. By...
This Project Grant award of $705,775 from the National Institute on Aging (CFDA 93.866 - Aging Research) supports a comprehensive study of mitochondrial diversity in the aging brain and immune system. The primary objectives are to: Generate high-resolution mitochondrial gene expression profiles ("mitotypes") for over 1.4 million brain cells and 0.9 million immune cells from older adults to identify mitochondrial recalibrations associated with age, sex, cognitive reserve, and...
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