This $138,000 Project Grant award from the National Institute on Aging's Aging Research Program (CFDA 93.866) will support the American Physiological Society's Integrative Physiology of Exercise (IPE) conference. The two-day conference, to be held in Fall 2024 at Pennsylvania State University in conjunction with the 50th anniversary of the Noll Laboratory, will focus on the future of human performance and aging research. Key topics will include the effects of aging and physical activity on...
This Project Grant award from the National Institutes of Health's National Institute on Aging (CFDA 93.866 - Aging Research) provides $2,496,057.49 to the University of Arizona to investigate the role of hepatic glucagon receptor signaling in healthspan and aging. The project aims to study the effects of genetic and pharmacological manipulation of glucagon receptor signaling on normal aging, obesity-accelerated aging, and the slowed aging resulting from calorie restriction. The research will...
This $270,000 Project Grant award from the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866) aims to provide comprehensive training in translational aging research and diverse career paths across academia, industry, and entrepreneurship. The award will support 15 doctoral or postdoctoral trainees over a 5-year period, enabling them to pursue research in aging while also gaining practical experience in various dimensions of translational research,...
This $654,238 Project Grant award from the National Institute on Aging (NIA) under CFDA Program 93.866 - Aging Research supports research to investigate the role of senescent cells in brain aging and the development of Alzheimer's disease and related dementias (ADRD). The project aims to generate high-resolution spatial omics data from ADRD brains and mouse models to identify molecular changes in the microenvironment of senescent neurons compared to healthy neurons. The work will be conducted by...
This Project Grant award of $395,796 from the National Institute on Aging's Aging Research program (CFDA 93.866) supports research at Brown University to develop genetic, pharmacological, and dietary interventions that delay the onset and progression of age-related diseases. The key objectives are to: 1) Investigate the interconnectedness and hierarchical structure of the hallmarks of aging, such as loss of genomic integrity, activation of retrotransposons, and accumulation of lipid droplets; 2)...
The National Institute on Aging (NIA) awarded a $125,896 Project Grant under the Aging Research program (CFDA 93.866) to The Washington University in St. Louis to conduct research on Alzheimer's disease (AD) risk and resilience pathways. The project aims to perform deep molecular characterization of AD genetic risk factors and protective mechanisms using state-of-the-art single-cell multi-omic analyses of healthy and AD human brain tissue, as well as transgenic AD mouse models. Key objectives...
This $1,031,595 project grant from the National Institute on Aging, part of the Department of Health and Human Services, supports research under the Aging Research program (CFDA 93.866). The awardee, Dana-Farber Cancer Institute, will define the landscape and mechanisms of protein redox regulation during aging. Specifically, the Institute will systematically map cysteine oxidation networks in mouse tissues to determine their role in coordinating protein complex assemblies relevant to age-related...
This Project Grant award from the National Institute on Aging (part of the Department of Health and Human Services) under CFDA 93.866 - Aging Research provides funding to the University of California, San Diego (UCSD) to conduct research on identifying mechanisms of adult neurogenesis, or the generation of new neurons in the aging brain. The $126,956 award aims to leverage single cell spatial transcriptomics technology to define the pathways by which glial cells (non-neuronal cells in the brain)...
This $485,375 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will fund research at the University of Washington to investigate genomic alterations in skeletal muscle associated with aging. The key objectives are to: Explore if alternative splicing of mRNA results in quantitative differential isoform changes associated with aging, potentially leading to increased expression of non-functional proteins relevant for healthy muscle function. The researchers...
This National Institute on Aging (CFDA 93.866 Aging Research) Project Grant award of $412,500 to the Trustees of Boston University (Boston University Medical Campus) will fund research to investigate the "vicious cycle" between disruption of chromatin architecture, activation of retrotransposable elements (RTEs), and misexpression of CpG island-deficient genes during the aging process. The research aims to validate the mutual activation between chromatin architecture disruption and RTE...
This $150,000 Project Grant from the Department of Health and Human Services' National Institutes of Health National Institute on Aging will support the Gerontological Society of America's Biological Sciences Section program at the 2021 Annual Scientific Meeting in Phoenix, Arizona from April 1, 2021 through March 31, 2022.
The program aims to highlight high-quality, translational aging research and promote exchange of information across disciplines through a single-track meeting program featuring emerging concepts in basic biology of aging. Fifteen non-competing oral sessions will be held, many suggested through an open call for proposals, to broaden topic and speaker selection. One speaker in many sessions will be selected from submitted abstracts, preferencing early career investigators. Two poster sessions will also be included. The program shows 30% of all speakers will be early career, nearly half of invited speakers are women, and 20% are from underrepresented minority groups. This Project Grant supports the Aging Research program's goal of greater understanding of aging and age-related diseases.