The National Institutes of Health (NIH) Office of the Director awarded a $320,799 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to the Mayo Clinic, a renowned non-profit academic medical center, for the project "Rare Variant Analysis Integrating Large Public DNA Sequencing Controls and Gene Expression Data for Discovering Novel Predisposition Genes of Orofacial Clefts." The goal of this project is to leverage genetic burden analyses, large control sample sizes, and transcriptomic data to identify novel genetic variants and predisposition genes associated with orofacial clefts, a common birth defect. The research aims to facilitate early diagnosis, risk stratification, and the development of targeted treatments for orofacial clefts. The award period runs from June 10, 2025, to May 31, 2026.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $320.8k | 6/10/25 |