The National Institute of Mental Health (NIMH) awarded a $156,500 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Emory University to identify patients with true treatment failure for major depressive disorder (MDD) who may benefit from earlier referral to alternative treatments like transcranial magnetic stimulation, ketamine, and vagus nerve stimulation. The project aims to use trajectory classification methods to empirically separate partial response from true treatment failure in patients who do not respond to first-line therapies like SSRIs, SNRIs, and CBT. This will help identify a group of patients more likely to have treatment-resistant depression (TRD) who could then be targeted for earlier referral to alternative treatments. The study will also demonstrate an analytic framework for future modeling of treatment failure using genetic biomarkers. The award period is from August 1, 2024 to July 31, 2026.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $156.5k | 7/17/24 |