Project Grant R61MH138647

Award Date 4/1/25
Completion Date 3/31/27
Dollars Obligated $969K
Federal Grant Program
93.242
Assistance Type
Project Grant
Place of Performance
California, USA
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The National Institute of Mental Health (NIMH) awarded a $968,769 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to the University of California, San Diego (UCSD) for the "MAINTENANCE RTMS FOR DEPRESSION (MAITR-DE)" project. This 2-year study aims to investigate the efficacy of maintenance repetitive transcranial magnetic stimulation (rTMS) in sustaining treatment response for individuals with treatment-resistant depression. Key objectives include examining the impact of standard and clustered maintenance rTMS on functional connectivity between brain regions and assessing clinical symptom maintenance. The project will be conducted across 3 study sites - UCSD, Cornell University, and Australian National University. The findings from this research are expected to provide insights into the most effective maintenance rTMS protocol and identify potential neurobiological markers to guide personalized treatment selection.

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