This federal Project Grant award of $968,769 from the National Institute of Mental Health (NIMH) under CFDA 93.242 Mental Health Research Grants will fund a study to investigate the efficacy of maintenance repetitive transcranial magnetic stimulation (rTMS) for individuals with treatment-resistant depression. The study will recruit 75 participants across three sites - the University of California San Diego, Cornell University, and Australian National University - into a double-blind, three-arm...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) aims to advance transcranial magnetic stimulation (TMS) technologies for the treatment of psychiatric disorders. The $382,480 award, granted on September 26, 2024, will support research to validate a closed-loop approach for prefrontal TMS using real-time electroencephalographic (EEG) recordings in a non-human primate model. The key objectives are...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $198,728 to The Trustees of the University of Pennsylvania to elucidate the mechanisms by which repetitive transcranial magnetic stimulation (rTMS) alters glutamate signaling and functional connectivity in the salience network, which may contribute to the antidepressant effects of this intervention. The project aims to leverage cutting-edge...
The National Institute of Mental Health (NIMH) awarded a $182,528 Project Grant under the Mental Health Research Grants (CFDA 93.242) program to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH). The grant, running from September 1, 2024 to August 31, 2028, will leverage MGH's multichannel transcranial magnetic stimulation (TMS) array system combined with electroencephalography (EEG) to simultaneously modulate and record activity across multiple nodes of...
This federal Project Grant award from the National Institute of Mental Health (CFDA 93.242 - Mental Health Research Grants) will fund a randomized double-blind clinical trial to test the superiority of bilateral accelerated theta burst stimulation (ATBS) compared to unilateral ATBS for treating suicidal ideation in individuals with treatment-resistant depression. The $197,576 award, effective September 1, 2024 through August 31, 2029, will allow researchers at the University of California, San...
This Project Grant award, funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program, aims to improve the understanding and treatment of depression. The $784,096 award to The Leland Stanford Junior University will develop optimized methods for measuring brain excitability in depression using repetitive transcranial magnetic stimulation (rTMS). Specifically, the project will: 1) investigate how adjusting rTMS parameters affects neural...
This federal Project Grant award of $830,409.00 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports the development of novel software and computational techniques that integrate real-time electric-field mapping and source-space electroencephalogram (EEG) analysis to improve the accuracy of transcranial magnetic stimulation (TMS) targeting and dosimetry for individualized treatment of brain diseases. The key products and...
The federal Project Grant award of $176,979.00 was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The award aims to develop personalized neuromodulation interventions that can effectively target and reduce social avoidance behavior (SAB) in patients with major depressive disorder (MDD) or social anxiety disorder (SAD). Specifically, the research will use transcranial magnetic stimulation (TMS) to causally modulate...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $781,464 to develop a "causal wiring diagram of transdiagnostic brain functions." The research aims to use brain stimulation technology and functional MRI to map causal brain circuitry associated with a range of mental health conditions, including major depression, obsessive-compulsive disorder, schizophrenia, and generalized...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $898,025 to the University of Cincinnati to evaluate the use of transcutaneous spinal direct current stimulation (tsDCS) to modulate spinal interoceptive pathways (SIPs) and assess their role and therapeutic potential in major depressive disorder (MDD). The award supports a two-phase research study. In the R61 phase, the researchers will use...