Project Grant R03HL183277
- The National Heart, Lung, and Blood Institute awarded the Trustees of Indiana University $277,375 under the Cardiovascular Diseases Research program (CFDA 93.837) on July 25, 2026, to conduct a cluster randomized controlled trial assessing the feasibility and effect of Health Strides, a six-month, multi-level physical activity intervention targeting Head Start staff. The intervention combines workplace-level and individual-level components. The workplace component establishes a wellness...
- The National Heart Lung and Blood Institute awarded Northwestern University $2,139,171 under Project Grant R01HL184083 on September 1, 2026, to conduct epidemiological and mechanistic research linking ectopic fat with inflammation and atherosclerosis. The research addresses gaps in understanding how distinct fat depots—hepatic, visceral, epicardial, and pericoronary—drive local vascular inflammation and coronary plaque formation across populations. Northwestern will leverage two...
- The National Heart, Lung, and Blood Institute awarded Northwestern University $2,162,045 under Cardiovascular Diseases Research (CFDA 93.837) on September 15, 2025, for research characterizing apolipoprotein proteoforms and their relationships with cardiometabolic health and coronary heart disease events. The research objective is to characterize the full spectrum of apolipoprotein post-translational modifications in human plasma and to quantify their associations with adiposity, insulin...
- The National Heart, Lung, and Blood Institute awarded Northwestern University $684,570 on July 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop and validate a bioengineered mitochondrial therapy platform for endothelial repair in vascular surgery. The research addresses endothelial injury, a fundamental barrier in vascular procedures that contributes to post-operative complications including vein graft failure, restenosis, and thrombosis. Northwestern's...
- The National Heart, Lung, and Blood Institute awarded Northwestern University $1,597,024 under the Cardiovascular Diseases Research program (CFDA 93.837) on July 1, 2026, to investigate mitochondrial quality control mechanisms in donor heart endothelial and smooth muscle cells as a strategy to improve cardiac allograft survival and reduce cardiac allograft vasculopathy following heart transplantation. The research addresses the acute and chronic phases of transplant injury:...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded Northwestern University a Project Grant of $793,184 on August 1, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct the AUTO2 Trial, a 2×2 factorial, patient-randomized controlled trial examining digitally-enabled home blood pressure monitoring strategies for patients with uncontrolled hypertension. The research will evaluate the comparative effectiveness of automated...
- The National Heart, Lung, and Blood Institute awarded Northwestern University $812,196 under the Cardiovascular Diseases Research program (CFDA 93.837) on August 15, 2026, to conduct research on targeted NAD+ replenishment as pre- and post-bypass therapy against vein graft failure. The research addresses the clinical problem that up to 20 percent of vein grafts fail within the first year following bypass surgery, and nearly half are occluded by 10 years. The award funds investigation of...
- Federal Grant Award Summary Northwestern University received a $259,729 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded September 15, 2025, with a completion date of June 30, 2027. The project, "Assessing and Decomposing Drivers of Disparities in Cardiovascular Health Outcomes in Sexual Minorities," delivers epidemiological research and quantitative analysis services examining...
- The National Heart, Lung, and Blood Institute awarded Northwestern University $120,000 on July 21, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) for Project Grant R21HL184309. The award funds development of probabilistic and explainable machine learning methods to predict technical success and stroke outcomes following mechanical thrombectomy for acute ischemic stroke patients with large vessel occlusion. Northwestern will develop state-of-the-art probabilistic models...
- The National Heart, Lung, and Blood Institute awarded Northwestern University $1,477,950 on September 10, 2025, under CFDA 93.837 (Cardiovascular Diseases Research) to conduct observational research defining the optimal interval for women to delay pregnancy after discontinuing long-acting glucagon-like peptide-1 receptor agonists (GLP-1 RAs). The research addresses evidence gaps in pregnancy and postpartum outcomes following GLP-1 RA discontinuation. GLP-1 RAs, now established therapies for...
The National Heart, Lung, and Blood Institute awarded Northwestern University $120,000 under Cardiovascular Diseases Research (CFDA 93.837) on August 13, 2026, for MITRA (Motivating Incentives to Increase Physical Activity), a project grant addressing low physical activity rates among South Asian adults with high cardiovascular disease burden. The project evaluates the acceptability of six behavioral economics-based intervention strategies—social incentives, gamification, commitment devices, motivational feedback, goal setting, and financial incentives—for increasing physical activity in South Asian adults. Aim 1 uses a theoretical framework-informed mixed methods questionnaire and best-worst scaling exercise to prospectively query intervention acceptability among South Asian adults with suboptimal physical activity levels; the two most acceptable strategies will be selected for advancement. Aim 2 pilot-tests the two selected strategies in a 2x2 factorial randomized trial design, evaluating primarily for feasibility and secondarily for additional endpoints. Performance takes place in Chicago, Illinois. The period of performance runs through July 31, 2028. This is a Project Grant assistance type awarded to Northwestern University's Sponsored Research Division.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $120.0k | 8/14/26 |