Project Grant R03HD119384
- This federal Project Grant award, valued at $107,838.00, was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The award will support research by Northwestern University to reconstruct the ancestral gene regulatory network underlying neural crest stem cells and pluripotent blastula stem cells in vertebrates. This work aims to advance the understanding of how stem cell attributes are controlled and how...
- This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), is providing $486,750.00 to the Sloan-Kettering Institute for Cancer Research, a non-profit organization, to conduct research on the molecular and cellular pathways that drive competency for human vagal neural crest specification. The research aims to fully characterize the population of cells that exhibits...
- The federal Project Grant award titled "NEURAL CREST REGULATION OF EMBRYONIC CALCIUM UPTAKE" was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The $200,625 award supports research at the Children's Hospital Medical Center in Cincinnati, Ohio to determine the role of neural crest cells in regulating calcium uptake and bone mineralization during vertebrate...
- This federal Project Grant award in the amount of $426,650 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The funding supports research by Trustees of Tufts College, doing business as Tufts University, to develop a hybrid strategy for efficiently deriving region-specific neural cell populations, including oligodendrocytes and neural crest progenitors,...
- This federal Project Grant award for $378,123 from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to identify and test mechanisms that establish transcriptional regulatory potency in early embryos. The primary activities include using genomic methods like PRO-seq, DREG, and OMNI-ATAC to characterize transcriptionally active regulatory elements, DNA accessibility, and...
- The federal Project Grant award titled "FROM CREST TO BONE: UNDERSTANDING NEURAL CREST SKELETOGENIC CAPACITY ALONG THE NEURAL AXIS" is funded by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121). The $162,281 grant, awarded on August 6, 2025, supports research at the California Institute of Technology (Caltech) to investigate the fundamental gene regulatory networks driving neural...
- This Project Grant award of $889,616.00 from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) supports research to investigate the cellular and molecular mechanisms by which specific RNAs and proteins enriched in neural crest cell (NCC) protrusions promote NCC migration. The research aims to determine the transcriptome and proteome of NCC projections and test their function, as well as examine the localization...
- This Project Grant award of $248,994 was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), which administers the Child Health and Human Development Extramural Research Federal Grant Program (CFDA 93.865). The award will fund research by the Washington University in New York, NY to investigate the mechanisms by which histone mutations affect chromatin structure, gene expression, and neural differentiation during development. The goal is to...
- The Project Grant award titled "Asymmetric RNA Segregation in Neural Stem Cells" was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The $392,004 grant will support research at the University of Washington to identify and characterize asymmetrically segregating RNA molecules in fly neural stem cells, with the goal of understanding how RNA partitioning contributes...
- This federal Project Grant award was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The $763,886 award, granted on March 12, 2025, supports a comprehensive research project at The Children's Hospital of Philadelphia (CHOP) to identify and functionally study RNA isoforms regulated by the ESRP1/2 proteins during epithelial-mesenchymal transition (EMT)....
This federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $160,000.00 to Northwestern University to conduct research on the "REGULATION OF NEURAL CREST FORMATION BY POU5F TRANSCRIPTION FACTORS." The research aims to advance the understanding of neural crest cells and their role in vertebrate development, with potential implications for addressing congenital defects and advancing regenerative medicine. The project will investigate the molecular mechanisms by which POU family transcription factors regulate neural crest formation, shedding light on the evolutionary origins and stem cell attributes of these critical cell types. The award has an initial funding period from August 12, 2025 to July 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $160.0k | 8/12/25 |