Project Grant R03HD111973
Award Date
9/22/23
Completion Date
8/31/25
Dollars Obligated
$163K
Federal Agency
National Institute of Child Health and Human Development
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Philadelphia, PA 19104, USA
Similar Awards
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), is focused on dissecting the input-output relationships of developmental BMP signaling. The $104,838 award to Duke University will support research that aims to shed light on how cells perceive and respond to varying BMP signaling inputs, with the goal of uncovering fundamental principles of cell...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will fund a research project to create integrated maps of cell state and lineage during normal mammalian development. The $125,000 award to the Whitehead Institute for Biomedical Research will leverage a prime editing-based technology called PETRACER to study progenitor cell dynamics in engineered mouse...
This $453,000 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) supports research to define the molecular mechanisms and cellular dynamics required to assemble a functional stem cell niche during embryonic development. The research, conducted at East Carolina University, aims to elucidate the signaling pathways, transcriptional regulators, and cytoskeletal processes that guide the migration and...
The National Institute of Child Health and Human Development (NICHD) awarded a $411,125 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Syracuse University to develop a microfluidic human placenta organoid model. The goal is to generate human trophoblast stem cells (HTSCs) from induced pluripotent stem cells and use them to create a placenta organoid system that can replicate early/mid-gestation placental development. The researchers will study the role of...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $760,617 to support research on understanding the mechanisms of pluripotency transitions during peri-implantation development. The award, which runs from April 2025 to January 2030, will fund work at Boston Children's Hospital to: 1) identify key transcription factors and dissect the mechanisms...
The National Institute of Child Health and Human Development (NICHD) awarded a Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Wayne State University for $989,586.00 on September 18, 2023. The purpose of the award is to conduct rapid, non-invasive biomechanical imaging of neural crest cell migration in vivo. The project will run through August 31, 2025. As a large, urban research university with extensive expertise in biomedicine and engineering, Wayne...
This $1,383,800 federal Project Grant award from the Department of Health and Human Services' National Institutes of Health, under the Trans-NIH Research Support (CFDA 93.310) program, supports the University of Pittsburgh's research to develop new methods for creating and testing developmental signaling patterns. The project aims to leverage high-throughput optogenetic manipulation to build libraries of paired data on developmental signaling patterns and resulting tissue structures. This...
The National Institute of Child Health and Human Development (NICHD) awarded a $413,843 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to The Pennsylvania State University, doing business as Penn State, to develop advanced biofabricated seminiferous tubules for in vitro spermatogenesis research. The proposed work aims to use micro-extrusion technology to precisely fabricate microtubes that mimic the cellular composition and organization of in vivo...
This federal Project Grant award in the amount of $132,460 from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research to investigate the molecular mechanisms underlying cellular heterogeneity in the ERK signaling pathway. The award, with a period of performance from December 1, 2024 to June 30, 2027, will be conducted at Princeton University. The research aims to...
The National Institute of Child Health and Human Development (NICHD) awarded Yale University a $921,250 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant funds a 2-year project to define the molecular pathways governing chromocenter restructuring before and after fertilization. The study aims to determine how the chromatin regulator DOT1L controls chromocenter disassembly during sperm nuclear condensation, as well as how DOT1L...