Project Grant R03DK142841
Award Date 9/15/25
Completion Date 8/31/27
Dollars Obligated $234K
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Oregon, USA
Similar Awards
- This federal Project Grant award of $630,847 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports research conducted by Children's Mercy Hospital in Kansas City, Missouri to study the role of the SIGIRR gene in regulating intestinal barrier function and preventing necrotizing enterocolitis (NEC) in preterm infants. The key focus areas include...
- This $232,500 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) aims to address the challenge of necrotizing enterocolitis (NEC), a life-threatening intestinal disease in premature infants. The grant will support research to define the efficacy of human-derived placental stem cell extracellular vesicles (HPSC-EV) as a potential cell-free therapy, determine the cellular and transcriptional changes in NEC disease and therapeutic repair, and...
- This federal Project Grant award, totaling $2,334,824.00, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The overriding goal of this 4-year grant, awarded to The Johns Hopkins University, is to understand the pathogenesis of neonatal necrotizing enterocolitis (NEC) - a leading cause of death from gastrointestinal disease in premature infants - and to develop...
- This $2,618,975 Project Grant was awarded on September 8, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The funding supports a 5-year research project led by the University of Texas Health Science Center at Houston to advance the development and functional capabilities of tissue-engineered intestine as a potential cure...
- This federal Project Grant award for $836,942 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research into the role of autophagy (self-digestion) in intestinal regeneration and stem cell activity. The research aims to investigate how autophagy contributes to injury resistance and the ability of certain intestinal cell types to re-acquire stem cell-like...
- This $2,970,076 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) aims to investigate the developmental programming of adult intestinal stem cells (ISCs) and how an obesogenic maternal environment during pre- and postnatal development can establish a maladaptive pre-pathological ground state in offspring. Using genetically engineered mouse and organoid models, the...
- This Project Grant award of $116,625 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research at the University of Iowa to investigate the epithelial-specific roles of the antioxidant protein Glutathione Peroxidase 1 (GPX1) in the intestinal microenvironment. The research aims to leverage the researchers' previous findings on the protective effects of GPX1...
- This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $164,700 to the University of California, Davis to investigate the mechanosensitive regulation of intestinal smooth muscle cell calcium signaling during gut development. The overarching goal is to improve understanding of the underlying mechanisms contributing to prematurity-related...
- This federal Project Grant award of $358,039 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is supporting research by Nous Biosciences Inc. to evaluate a combination therapy of dolcanatide (a guanylate cyclase-C agonist) and atiprimod (a JAK-STAT inhibitor) for the treatment of murine colitis. The research aims to advance understanding of the pathogenesis of...
- This $164,188 federal Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The 5-year grant supports training and research at the University of Washington to study the role of intestinal chondroitin sulfate glycosaminoglycans in inflammatory bowel disease. The research aims to determine how changes in the composition of these gut matrix...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $234,000 in funding to Oregon Health & Science University to support research on the role of the IMP1 protein in regulating intestinal mucus composition and promoting survival during necrotizing enterocolitis (NEC) in premature infants. The project aims to define the impact of IMP1 expression on intestinal mucus glycosylation and permeability, and to determine the requirement for the QSOX1 enzyme in IMP1-mediated survival during NEC. The award period runs from September 15, 2025 to August 31, 2027.
Generated 10/21/25, 5:59 AM
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $234.0k | 9/4/25 |