Project Grant R03DE036072
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $317,000 Project Grant to The Research Foundation For The State University of New York (Stony Brook University) on August 7, 2025, under the Oral Diseases and Disorders Research program (CFDA 93.121). This two-year research initiative, concluding August 6, 2027, focuses on chemoprevention strategies for oral squamous cell carcinoma (OSCC) promoted by electronic cigarette exposure. The...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded the University of Pittsburgh a $1.9M Project Grant (CFDA 93.121: Oral Diseases and Disorders Research) effective September 19, 2025, through September 18, 2028, to conduct computational and experimental research analyzing high-dimensional genomic datasets from human head and neck squamous cell carcinomas (HNSCC). The project will employ systems biology modeling and novel analytical...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded $440,275 on July 9, 2026, through its Oral Diseases and Disorders Research program (CFDA 93.121) to support a two-year research project investigating sex-based differences in radiation-induced oral mucositis (OM) pathophysiology. The Research Foundation for the State University of New York, administering through its Sponsored Projects Services division, serves as the fiscal agent for...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded $422,125 in funding through its Drug Use and Addiction Research Programs (CFDA 93.279) to the University of Nebraska Medical Center to conduct epidemiological research on oral nicotine pouch (ONP) use among adolescents and young adults (AYAs). The award, effective July 1, 2026 through June 30, 2028, supports a two-year study harmonizing nationally representative survey and biomarker data from waves 7-9...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded $540,629 to the University of Massachusetts Lowell on August 15, 2025, under the Oral Diseases and Disorders Research program (CFDA 93.121) to support research investigating human oral host-pathogen interactions and dysbiosis modulation. The project, scheduled for completion by August 14, 2027, focuses on developing and validating an immunocompetent three-dimensional (3D) in vitro model...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $219,660 Project Grant to the Regents of the University of Michigan, effective January 1, 2029, under the Oral Diseases and Disorders Research program (CFDA 93.121). This research initiative, titled "Intercepting the Evolution of Pro-Tumoral Myeloid Cells During the Initiation of Oral Cancer," delivers preclinical research services focused on understanding the immunological...
- Federal Project Grant Award Summary The National Institutes of Health Office of the Director awarded $819,998 to The Regents of the University of California, San Francisco under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077) on August 1, 2026, with a completion date of July 31, 2029. This clinical pharmacology research project will investigate the human health effects and nicotine exposure profiles associated with oral nicotine pouches (ONPs),...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research awarded $870,334 under the Oral Diseases and Disorders Research program (CFDA 93.121) to The Research Foundation for the State University of New York for a project spanning August 1, 2025, through July 31, 2027. The project focuses on developing an early tooth organoid utilizing human induced pluripotent stem cells (iPSCs), addressing a critical gap in understanding early tooth development. The research...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $1.47 million Project Grant to the University of Texas MD Anderson Cancer Center on March 1, 2026, under the Oral Diseases and Disorders Research program (CFDA 93.121). The five-year award, extending through February 28, 2031, supports research to elucidate subclonal evolution and fitness dynamics in oral carcinogenesis. The project addresses the significant clinical challenge that...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $315,000 Project Grant to The University of Texas Health Science Center at San Antonio effective August 20, 2025, through August 19, 2027, under the Oral Diseases and Disorders Research program (CFDA 93.121). This award supports research to develop and validate a novel therapeutic approach targeting Transient Receptor Potential Canonical 1 (TRPC1) channels as a treatment for oral...
Health Research, Inc.'s Roswell Park Division was awarded $347,000 by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) on July 8, 2026, with a completion date of July 7, 2028. The award funds a large-scale, population-based research study examining the impact of reduced-exposure nicotine products on oral health conditions among high-risk populations in the United States. Specifically, the project will evaluate how electronic nicotine products (ENPs) and oral nicotine pouches—which expose users to fewer harmful constituents than combustible tobacco—affect oral health outcomes among the estimated 8.5 million former tobacco users who have adopted these products. The research deliverables include a comprehensive population-level analysis using an empirically-driven conceptual model to assess oral health impacts while controlling for co-occurring risk factors and protective factors. This investigation addresses a critical gap in the scientific literature, as the growing market adoption of reduced-exposure nicotine products among former smokers and smokeless tobacco users requires evidence-based evaluation of their oral health consequences. The findings will inform public health policy and clinical guidance regarding nicotine product use and oral disease prevention, particularly for vulnerable populations at heightened risk of oral health conditions.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $347.0k | 7/10/26 |