This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) aims to elucidate the link between oral health and different subtypes of dementia, including Alzheimer's disease (AD) and vascular dementia (VAD). The total award amount is $1,530,868 and the project period runs from August 15, 2024 to April 30, 2029. The key research objectives are to: 1) establish the relationship between poor oral health and clinical biomarkers of dementia, and the incidence of AD and...
This Cooperative Agreement award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $3,465,577.00 to examine the influences of socioeconomic stressors and education-related opportunities on oral health outcomes among a diverse cohort of emerging adults. The project aims to: 1) assess the impact of early adulthood socioeconomic factors on oral health over time, 2) examine how education-related...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, provides $198,000 to The Pennsylvania State University (Penn State) to conduct research on the relationship between oral microbiome diversity and oral health disparities in the United States. The key objectives are to: 1) Analyze how oral microbiota diversity, composition, and abundance of individual species differ across...
This $431,750 federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) supports research to decipher the mechanisms by which two proteins, AAFLP-1 and AADCUB, regulate the production of exopolysaccharide (PNAG) in the oral bacterium Aggregatibacter actinomycetemcomitans. The research aims to investigate how these two proteins, which are unique to A. actinomycetemcomitans, independently...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a Project Grant (CFDA 93.121 - Oral Diseases and Disorders Research) in the amount of $473,632 to the University of Toledo on May 1, 2025. The purpose of this 3-year project is to investigate the role of megakaryocytes (MEGs) and their response to the cytokine interleukin-17 (IL-17) in oral mucosal immunity, particularly during oropharyngeal candidiasis caused by Candida albicans. The research aims to elucidate the...
This $515,926 Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) will fund research to develop an in vitro gingival (gum) tissue system to study the role of microbial communities on oral health and disease. The 5-year project, beginning June 1, 2024, will be conducted by the University of Massachusetts Lowell's Office of Research Administration-Lowell. The key objectives are: (1) developing and validating a microphysiological system to study oral...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121), provides $234,000.00 to Oregon Health & Science University (OHSU) to develop new genetic tools and methods to study the Prevotella genus of oral bacteria. The key objectives are to: 1) Characterize the natural competence ability of oral Prevotella species, and 2) Develop a comprehensive genetic toolbox to...
This federal Project Grant award of $185,918, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), will fund research to evaluate the impact of Medicaid coverage for the treatment of periodontal disease on health outcomes. The key objectives are to assess the effect of Medicaid coverage for periodontal treatment on tooth loss, emergency department use for dental problems, oral healthcare costs, and...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $999,776.00 to the University of Utah to advance oral health equity through integrated patient, provider, and population-based research approaches. The goal is to strengthen the scientific basis for innovative population-level strategies to improve dental care access, utilization, and quality, particularly for...
The University of Texas Health Science Center at Houston received a $722,040 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121). The grant, titled "FULLMOUTH: Enhancing Dental Clinical Data and Reducing Disparities Through Innovative ML Approaches", aims to utilize natural language processing and machine learning techniques to extract meaningful insights from...