Project Grant R03AG095804
- This $2,356,117 federal Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) will support research to improve the perioperative management of patients with Alzheimer's disease and related dementias. The primary objectives are to: (1) identify the extent to which surgical patients with these conditions are at increased risk for adverse postoperative outcomes, and (2) estimate the association between various perioperative interventions and the incidence...
- The University of Pittsburgh received a $801,268 Project Grant award from the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866). The objective of this 5-year award, with a start date of June 1, 2025, is to develop an effective evidence-based approach to providing value-based perioperative care in high-risk elderly surgical patients. The project aims to improve prediction and prevention of postoperative mortality, delirium, cognitive decline, and other...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to the University of Florida provides $383,750.00 to investigate the role of age-associated immune modulation and cellular senescence in the progression of papillary thyroid carcinoma in older adult patients. The key objectives are to: (1) identify the contribution of advanced age to the senescence-associated secretory phenotype (SASP) in thyroid tissue, and (2) characterize alterations in the...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $624,000.00 to the University of Texas Health Science Center at Houston to explore a patient priorities care framework for improving breast cancer survivorship care for older women with multiple chronic conditions. The project aims to use this framework to identify patient priorities, incorporate them into treatment plans, and evaluate the feasibility and impact on treatment burden and quality...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) is for the research project "Impact of Hypertension and Aging on Postoperative Delirium". The $715,801 grant, awarded on June 1, 2025, supports Duke University's research to elucidate the contributions of endothelial cells and perivascular macrophages to surgery-induced neuroinflammation, blood-brain barrier disruption, and delirium-like behavior in aging and hypertension. The overarching...
- This $146,070 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support research to investigate how the accumulation of senescent cells and their secretory phenotypes impact osteocyte mechanobiology in a 3D bone-mimicking microenvironment. The goals are to: (1) acquire experimental skills and career training to expand the researcher's program into cellular aging/senescence and molecular biology; (2) investigate how local vs. systemic senescent cells and...
- This Project Grant award of $243,000.00 from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to equip Dr. Canales with the necessary training and mentored research experience to emerge as a leader in perioperative aging research. The overarching goal is to conduct a pilot pragmatic randomized controlled trial of the Perioperative Care Partner Program (PCPP) in older adults undergoing major surgery. The PCPP combines established strategies for risk reduction and early...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $317,120 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to The Regents of the University of California, San Francisco (UCSF). The grant supports a research project to evaluate the use of parathyroid gland allotransplantation as a novel treatment approach for chronic hypoparathyroidism, a rare and debilitating condition characterized by low serum...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), CFDA 93.865 Child Health and Human Development Extramural Research program, aims to address the high rate of hypocalcemia (low blood calcium) following thyroidectomy (thyroid gland removal) in the pediatric population. The $1,000,028 award to Vanderbilt University will fund research to characterize the near-infrared autofluorescence (NIRAF) properties of parathyroid glands...
- This $225,000 Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) will support research to understand the biological mechanisms underlying calcium pyrophosphate deposition disease (CPPD), a common yet understudied age-related joint disease affecting over 30 million people worldwide. The research aims to develop advanced animal models to study CPPD disease progression and identify potential molecular pathways and therapeutic interventions. By elucidating the...
This federal Project Grant award of $415,000 from the National Institute on Aging (CFDA 93.866 Aging Research) supports research to improve surgical decision-making for older patients with primary hyperparathyroidism (PHPT). The key objectives are to: Develop predictive models for complications related to parathyroidectomy surgery in older adults, considering factors like age and frailty status. These models will be validated in a large national cohort. Evaluate the unique priorities and values that shape patient and provider decision-making around parathyroidectomy for this demographic. The grant was awarded to the University of Texas Southwestern Medical Center, a prominent academic medical research institution, to conduct this work over a 2-year period from September 2025 to August 2027. The findings aim to enhance surgical care and outcomes for older adults with PHPT, a common calcium metabolism disorder that can lead to serious health issues if left untreated.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $415.0k | 8/29/25 |