Project Grant R01NS150283
- The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, awarded Tulane University $625,392 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds investigation of microglial activation and inflammatory cytokine secretion as mechanisms driving central nervous system consequences of intermittent pathogen exposure. The recipient will investigate viral...
- The National Institute of Neurological Disorders and Stroke awarded Tulane University (The Administrators of Tulane Educational Fund) $1.234776 million on September 9, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop and evaluate nanoencapsulated painless nerve growth factor (NGFp) for treatment of spinal cord injuries. The project applies a double-encapsulation nanotechnology platform to deliver NGFp across the...
- The National Institute of Neurological Disorders and Stroke, a component of the Department of Health and Human Services National Institutes of Health, awarded $232,605 to the University of Pennsylvania on July 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), a Project Grant assistance type. The recipient will isolate and characterize microglial-derived extracellular vesicles as biomarkers for traumatic brain injury. The...
- The National Institute of Neurological Disorders and Stroke awarded the University of Texas Medical Branch at Galveston $161,500 on June 8, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop an inducible mouse model investigating the role of Z-DNA binding protein 1 (ZBP1) in neuroinflammation following traumatic brain injury. The project will generate a transgenic mouse model in which expression of a ZBP1 variant...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, will fund research at the Augusta University Research Institute, Inc. (doing business as Georgia Health Sciences) to investigate the mechanisms linking traumatic brain injury (TBI) to subsequent neurodegeneration and dementia. The $1,975,262 award will support a 3-year study...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services National Institutes of Health, awarded The Medical University of South Carolina $100,228 on December 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research on complement-mediated mechanisms of injury and repair in germinal matrix hemorrhage, a leading neurological injury of prematurity....
- The National Institute of Neurological Disorders and Stroke awarded Vanderbilt University Medical Center $262,500 on April 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop and validate a predictive tool for recovery of consciousness in acute traumatic brain injury. The research addresses the clinical challenge of prognosis in severe TBI, where decisions to continue neurorehabilitation or withdraw life-sustaining...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded The University of Kentucky Research Foundation $192,500 on February 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate chronic neurovascular dysfunction following repetitive mild traumatic brain injury. The funded research examines how repetitive mild blast TBI...
- The National Institute of Neurological Disorders and Stroke awarded the University of Texas Health Science Center at Houston $429,000 on April 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853, Assistance Listing R21NS142863). The award funds research into the role of skull bone marrow neutrophils in delayed neurological decline following aneurysmal subarachnoid hemorrhage. The project investigates why skull neutrophils respond...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded Yale University $667,613 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research examining ferroptosis—iron-induced programmed cell death—in erythrocytes within intracerebral hemorrhage hematomas. The project investigates how heme induces...
The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded The Administrators of Tulane Educational Fund (Tulane University) $474,321 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders grant program (CFDA 93.853). The award funds research investigating the role of the mitochondrial citrate transporter SLC25A1 in acute pro-inflammatory activation of microglia and brain-infiltrating macrophages following traumatic brain injury. The research examines how dysregulated cellular metabolism contributes to post-TBI inflammatory responses and tests whether SLC25A1 inhibition can restore mitochondrial bioenergetics, reduce pro-inflammatory activation, and attenuate neurodegeneration and neurological deficits. The project encompasses three specific aims investigating SLC25A1 activation's role in regulating mitochondria-to-cytosol citrate flux and mitochondrial bioenergetics. Performance will occur in New Orleans, Louisiana over the five-year period from September 1, 2026, through August 31, 2031. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $474.3k | 8/14/26 |