Project Grant R01NS146649
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded The Administrators of Tulane Educational Fund (Tulane University) $474,321 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders grant program (CFDA 93.853). The award funds research investigating the role of the mitochondrial citrate transporter SLC25A1 in acute pro-inflammatory activation...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $711,256 to the University of Arizona on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research defining how neurons drive outcomes in CNS toxoplasmosis caused by Toxoplasma gondii. The research addresses a mechanistic gap in understanding neuron-T....
- The National Institute of Neurological Disorders and Stroke awarded the University of Massachusetts Medical School $551,557 on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate nucleic acid sensing pathways in demyelinating disease. The funded research dissects the role of endosomal toll-like receptors (eTLRs) in neuroinflammation and demyelination, specifically examining how aberrant eTLR signaling in...
- The National Institute of Neurological Disorders and Stroke awarded Yale University $138,664 on February 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the long-term effects of intracerebral hemorrhage on behavior and neuroinflammation. The project employs an in-vivo mouse model of intracerebral hemorrhage using collagenase injection to map microglial activation and behavioral changes following stroke. Research...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded Wake Forest University $533,623 on September 3, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research investigating mechanisms that protect neurons from glutamate excitotoxicity during metabolic stress. The research uses avian neurons, which naturally resist...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services National Institutes of Health, awarded The Medical University of South Carolina $100,228 on December 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research on complement-mediated mechanisms of injury and repair in germinal matrix hemorrhage, a leading neurological injury of prematurity....
- The National Institute of Neurological Disorders and Stroke awarded Tulane University (The Administrators of Tulane Educational Fund) $1.234776 million on September 9, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop and evaluate nanoencapsulated painless nerve growth factor (NGFp) for treatment of spinal cord injuries. The project applies a double-encapsulation nanotechnology platform to deliver NGFp across the...
- The National Institute of Neurological Disorders and Stroke awarded the University of Miami $581,794 on September 7, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research into inflammasome activation and its role in the foreign body response triggered by chronically implanted microelectrodes in neural tissue. Microelectrode implants enable neuroprosthetic and neuromodulation technologies for patients with...
- The National Institute of Neurological Disorders and Stroke awarded $242,250 to the University of Virginia on February 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award funds research into myeloid cell regulation of cerebrovascular tone and function, specifically investigating how microglia and perivascular macrophages maintain baseline vascular structure and blood flow in the brain and facilitate vascular responses...
- The National Institute of Neurological Disorders and Stroke awarded $588,794 to the University of South Florida on July 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research investigating the functions of microglial laminin in blood-brain barrier repair and microglial activation following ischemic stroke. The research encompasses three aims: examining the function of microglial laminin in stroke...
The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, awarded Tulane University $625,392 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds investigation of microglial activation and inflammatory cytokine secretion as mechanisms driving central nervous system consequences of intermittent pathogen exposure. The recipient will investigate viral infection contributions to long-term brain and behavioral function in normal and neurodegenerative disease mouse models, characterize transcriptional and epigenetic profiles of pathogen-exposed cell populations in the brain, and interrogate microglia and inflammatory cytokines as drivers of neurological consequences. Research outputs address how chronic neuroinflammation represents a convergence point through which diverse pathogen subtypes induce effects on brain function and disease vulnerability. Performance occurs in New Orleans, Louisiana, through August 31, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $625.4k | 8/31/26 |