Project Grant R01NS140655
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program provides $310,834 to Clemson University to develop a nanoparticle-based platform for targeted, non-invasive delivery of therapeutics to the peripheral nervous system. The goal is to improve treatments for peripheral nerve injuries and diseases by overcoming the blood-nerve barrier that...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $151,559 to Rensselaer Polytechnic Institute (RPI) from August 3, 2024 to July 31, 2026. The project aims to develop innovative magnetically responsive drug delivery electrospun fibers to improve regeneration after spinal cord injury (SCI). Specifically, the research will focus...
- The National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), awarded a $184,837 Project Grant to The Ohio State University on April 25, 2025. The grant supports research on promoting spinal cord repair using a polymer-based drug delivery system. The project aims to investigate the use of targeted intraspinal delivery of gabapentinoids, a class of drugs that can promote axon...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $427,625 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of Washington. The project aims to explore whether electrical stimulation can enhance the effectiveness of neural stem cell transplants in improving recovery from chronic spinal cord injury. The research will investigate if combining these two promising treatments can produce...
- This $341,958 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA 93.853, Extramural Research Programs in the Neurosciences and Neurological Disorders, aims to investigate the regulation of nociceptor excitability by Macrophage Migration Inhibitory Factor (MIF) as a potential therapeutic strategy for treating chronic neuropathic pain after spinal cord injury (SCI). The 5-year research project, awarded to the University of Texas Health Science...
- This $961,052 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) aims to develop a nanoparticle-encapsulated siRNA formulation targeting the Fidgetin-like 2 (FL2) protein to promote tissue repair and functional recovery after spinal cord injury. The awardee, Microcures Inc., will conduct proof-of-feasibility studies in a rat contusion model to evaluate...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $566,382 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Temple University. The 5-year grant, effective August 15, 2025, will support research to investigate novel therapeutic strategies for restoring sensory connections in the spinal cord after dorsal root injuries. The research aims to determine if specific subtypes of sensory axons prematurely...
- This $506,696 Project Grant award was made by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award supports research at the University of Washington to examine the differential microvascular response to spinal cord trauma in the aging population. The research aims to evaluate critical microvascular blood flow parameters that can reduce cervical...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will fund research at the University of Louisville to investigate the role of propriospinal neurons in spinal cord injury recovery. The $462,296 award, with a period of performance from June 3, 2025 to May 31, 2030, will enable the researchers to use advanced tools like virus-based...
- This Project Grant award of $1,188,230 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to evaluate the cellular composition, activation state, and spatial niches involved in neuroma formation following severe peripheral nerve injuries. The primary goals are to validate preliminary data indicating that neutrophil extracellular traps (NETs) may be an...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), provides $624,329 to Tulane University to develop an efficient delivery system for a painless nerve growth factor (NGF) variant to treat spinal cord injuries. The project aims to encapsulate the NGF variant in a nanotechnology platform for improved penetration into the central nervous system, prolonged bioavailability, and reduced nociceptive response. The award period runs from September 9, 2025 to July 31, 2030, with the goal of advancing treatments to limit secondary injury and promote neuroregeneration for spinal cord injury patients, including those with severe battlefield injuries.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $624.3k | 9/9/25 |