Project Grant R01NS147518
- Federal Project Grant Award Summary Baylor College of Medicine received a $621,065 Project Grant from the National Institute of Neurological Disorders and Stroke under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective August 1, 2025, through July 31, 2030. The grant supports the development of advanced genetically encoded voltage indicators (GEVIs) optimized for two-photon resonant scanning microscopy applications. The primary...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $250,000 to the Trustees of Boston University on February 23, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program to develop and deliver a two-week summer school program in neurovascular imaging across scales in animals and humans. The program, operated by the Boston University Neurophotonics Center, will provide hands-on...
- Federal Project Grant Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Boston University $465,500 on July 5, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program to develop a novel closed-loop deep brain optoacoustic stimulation (DBOAS) technology platform. The award supports the design, validation, and preclinical evaluation of a multiple functional fiber-based optoacoustic emitter (MFOE) that...
- Federal Grant Award Summary Boston University received a $749,227 Project Grant from the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) awarded on May 15, 2025, for the acquisition and establishment of a three-photon microscopy system as a shared facility within the university's Neurophotonics Center. The three-photon microscope provides advanced fluorescence and phosphorescence lifetime imaging capabilities, enabling researchers...
- Federal Grant Award Summary Massachusetts Institute of Technology (MIT) received a $651,069 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded May 2, 2026, with completion targeted for April 30, 2031. The award supports development and advancement of spatially multiplexed imaging technology for visualizing complex cellular signaling networks in...
- Federal Project Grant Award Summary Boston University Medical Campus received a $647,496 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective June 1, 2026 through May 31, 2031. This five-year award supports fundamental neuroscience research investigating the role of neural precursors in fetal cortical development, specifically examining...
- Federal Grant Award Summary Boston University received a $1,926,960 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded September 15, 2025, with completion targeted for August 31, 2029. The grant funds development of robust, high-throughput superresolution (SR) imaging technology based on speckle illumination to address critical limitations in current fluorescence microscopy methods....
- Federal Project Grant Summary Massachusetts Institute of Technology received a $2.72 million Project Grant from the National Institute of Neurological Disorders and Stroke under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) for the period August 1, 2025 through July 31, 2028. The project focuses on developing high-speed complementary metal-oxide-semiconductor (CMOS) image sensors with pixel-wise programmable...
- Federal Project Grant Award Summary Boston University Medical Campus received a $159,104 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective February 12, 2026, through November 30, 2028. The award funds fundamental neuroscience research investigating how the primary motor cortex (M1) flexibly controls different movement types in...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Baylor College of Medicine a $1,265,552 Project Grant, effective August 1, 2025 through April 30, 2030, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This award supports fundamental research to advance understanding of astrocyte physiology—specifically the electrical properties of astrocytes and their coordination with...
Boston University received a $595,774 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective June 1, 2026, through May 31, 2031. The award funds development of advanced far-red microscopy technologies and genetically engineered voltage indicators (GEVIs) designed to enable high-speed voltage imaging of large neuronal populations in deep brain tissue. Boston University will deliver two complementary microscope systems—a large-field-of-view imaging system utilizing targeted illumination and confocal line-scanning (TICO2) and a prism-based multiplane imaging system (MULTI-P) employing inter-plane deconvolution—optimized for kilohertz-rate imaging with high signal-to-background ratios across multiple cortical layers in mouse brain tissue. In parallel, the institution will develop a novel class of fully genetically encoded, far-red GEVIs (FAR-OUT) based on rhodopsin proteins engineered through site-directed mutagenesis to exhibit enhanced brightness and far-red spectrum characteristics that enable improved tissue penetration and signal detection. The project culminates in in-vivo mouse imaging experiments that validate the performance of the newly developed microscopes and voltage indicators, demonstrating the capability to achieve high signal-to-noise ratio voltage imaging of hundreds of neurons and perform dense volumetric imaging of dendritic arbors, ultimately providing the neurophysiology research community with advanced tools for studying neural circuits at unprecedented scales and depths.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $595.8k | 6/3/26 |