Project Grant R01NS146023
- This $488,232 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, is funding research by The Washington University to explore the mechanisms by which astrocytes, a type of glial cell, support the metabolic needs of neighboring neurons in the brain. The 5-year project aims to investigate the regulation of intracellular and...
- This federal Project Grant award of $446,126 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a new bioassay to study astrocyte borders and profile their functional states in the context of diverse non-neural cell populations. The key objectives are to optimize the bioassay by combining injectable cellulose-based hydrogels with viral vectors to...
- This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $361,975 to support research focused on developing chemical strategies for imaging and manipulating astrocytes in the brain. The project aims to expand the capabilities of an astrocyte-targeting chemical tag to enable direct visualization and modulation of astrocyte...
- This federal Project Grant award of $141,102 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative program (CFDA 93.372). The award supports research by New York University to study the role of astrocyte networks in facilitating neuroplasticity. Key objectives include mapping functional astrocyte networks across the brain using a novel biotinylation...
- This federal Project Grant award of $370,462 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award supports research at Baylor College of Medicine in Texas to develop technical capabilities for studying brain state changes related to arousal and attention in mice and non-human primates. The research aims to advance the understanding of how brain...
- This Project Grant award, totaling $429,000.00, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award will fund research at Oregon Health & Science University (OHSU) to investigate the fundamental interactions between astrocytes and oligodendrocytes, two major types of glial cells in the central nervous system, and how these...
- This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $499,979 to The Salk Institute for Biological Studies to conduct research aimed at "Uncovering Astrocyte Contributions to Neuropathic Pain". The research project seeks to better understand the role of astrocytes, a type of glial cell in the central nervous system,...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) provides $168,455 to New York University School of Medicine to investigate region-specific factors in reactive astrocytes during neuroinflammation. The research project aims to explore the heterogeneous responses of astrocytes, the most abundant brain glial cells, to inflammation, focusing on...
- This Project Grant award of $621,065 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will fund the development of advanced genetically encoded voltage indicators (GEVIs) optimized for two-photon microscopy. The goal is to create GEVIs with improved sensitivity for detecting subthreshold signals and enhanced response kinetics to reliably capture rapid action potentials...
- This federal Project Grant award of $578,701, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to develop a new high-speed 3D voltage imaging microscopy system capable of capturing real-time neuronal activity over extended periods. The research, conducted by the University of California, Los Angeles (UCLA), aims to overcome the limitations...
This $632,776 federal Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) aims to fundamentally advance the understanding of astrocyte physiology. The grant supports research at Baylor College of Medicine to use novel genetically encoded voltage indicators (GEVIs) to measure astrocyte membrane potential and local neural activity in the mouse visual cortex. Key objectives include characterizing the coordination of astrocyte membrane voltage fluctuations and neural activity, determining how neuromodulatory inputs shape astrocyte voltage, and developing improved astrocyte-optimized GEVIs. This grant funding will enable critical investigations into the "electrical dimension" of astrocyte function and its relationship to neural activity, with the goal of transforming our understanding of glial-neuron interactions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $632.8k | 7/31/25 |