Project Grant R01NS147345
- Summary of Federal Project Grant Award The University of Cincinnati's Sponsored Research Services Division received a $669,092 Project Grant award dated May 15, 2025, from the National Institute of Neurological Disorders and Stroke under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The METABOL-ICH (Metabolomics of ICH Recovery) project will conduct comprehensive metabolomic analysis on plasma samples from 1,273 intracerebral hemorrhage...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded the University of Pittsburgh a $2.35 million Project Grant on September 8, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853). The award, which extends through June 30, 2029, funds research investigating the role of the SPAK-NKCC1 protein complex in blood-cerebrospinal fluid (blood-CSF) barrier dysregulation associated with vascular...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $438,625 to the University of California, San Diego under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) on August 7, 2025, for an exploratory research project extending through July 31, 2027. This project grant supports basic and translational neuroscience research aimed at characterizing a novel pro-survival mechanism in neurons exposed...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $521,839 Project Grant to the University of California, San Diego under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program on August 7, 2025. The award supports a five-year research initiative (through July 31, 2030) investigating the molecular mechanisms of pathogenic microglial populations in central nervous system (CNS)...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $149,264 Project Grant to Indiana University Indianapolis on December 5, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. This research initiative, with a completion date of May 15, 2027, investigates the mechanisms by which neutrophils contribute to cognitive decline in a comorbid model of Alzheimer's Disease (AD)...
- Federal Grant Award Summary The University of Michigan received a $633,146 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective August 4, 2025, with completion targeted for July 31, 2030. The award funds research to identify modifiable factors that reduce vascular cognitive impairment and dementia (VCID) risk in stroke survivors. The...
- Federal Grant Award Summary The University of Colorado-Denver received a $180,249 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, awarded on July 23, 2025, with a completion date of November 30, 2026. This award supports investigator-initiated research investigating the mechanisms and impact of amyloid-beta mediated disruption of synaptic...
- Federal Grant Award Summary The University of Cincinnati's Sponsored Research Services Division received a $445,500 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective August 1, 2025 through July 31, 2027. The award supports basic neuroscience research investigating the role of perinatal testosterone in programming behavioral and...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $599,005 project grant to the University of Miami's Office of Research Administration on August 21, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The research will be conducted in Florida and is scheduled for completion by July 31, 2030. This award supports investigator-initiated basic and translational research...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded the University of Wisconsin–Madison a Project Grant totaling $494,240 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective February 16, 2026, through January 31, 2031. This award funds a five-year research investigation into microRNA (miRNA) degradation mechanisms in post-stroke brain tissue, specifically examining...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded the University of Cincinnati $654,628 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program on March 6, 2026, for a project period extending through February 28, 2031. The award supports proteomics research investigating cognitive decline following intracerebral hemorrhage (ICH), specifically examining the relationship between peripheral blood protein signatures and post-ICH vascular contributions to cognitive impairment and dementia (VCID). The research leverages biospecimens and long-term cognitive outcomes from the Recovery of Stroke, Longitudinal Assessment with Neuroimaging (ROSE-LAWN) study, the largest and longest longitudinal study of ICH outcomes, which tracks 250 ICH patients over an extended assessment period beginning approximately 36 months post-ICH. The project will characterize the plasma proteome at the time of ICH using the SomaScan assay and analyze immune cell intracellular proteome to identify biomarker candidates and therapeutic targets for post-ICH VCID. By examining the association between systemic proteomic profiles and cognitive outcomes, this research aims to elucidate mechanisms underlying dementia risk following ICH and support development of preventive and treatment strategies for a condition that carries the highest dementia risk among stroke survivors.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $654.6k | 3/5/26 |