Project Grant R01NS144158
Award Date 8/7/25
Completion Date 7/31/30
Dollars Obligated $522K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
California, USA
Similar Awards
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $104,433 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Washington University in St. Louis to conduct research on examining microglia reactivation in multiple sclerosis (MS). The project aims to define the gene signature of disease-associated microglia (DAM) and understand how the function of these cells is affected by repeated activation, as...
- This $198,928 Project Grant was awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The grant will support research at the University of California, San Francisco to elucidate the cellular mechanisms underlying central nervous system injury and progression in multiple sclerosis. Key objectives include determining the role of astrocyte response,...
- This federal Project Grant award of $427,104.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is focused on identifying biomarkers of demyelination and remyelination in a mouse model of multiple sclerosis (MS). The key objectives are to profile proteins and lipids in tissue-derived and plasma-derived extracellular vesicles to discover novel biomarkers...
- This $374,749 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at Boise State University to investigate the role of FOXO1, NMMLCK, and HDAC6 in blood-brain barrier dysfunction and disease progression in multiple sclerosis. The research aims to identify mechanisms governing blood-brain barrier function and evaluate their therapeutic...
- This federal Project Grant award of $654,287.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The goal of the project is to develop a computational model of neurocognitive impairment in multiple sclerosis (MS), focusing on updating the outdated framework used to characterize cognition in MS. The project aims to leverage cognitive psychology and...
- This $4,164,187 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to develop antigen-directed therapies for autoantibody associated neuroinflammatory diseases. The project aims to facilitate the discovery of autoantibodies directed to cell surface antigens, characterize their specificity, and generate recombinant human...
- This $263,892 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) aims to evaluate the use of oral N-acetylglucosamine (GlcNAc) as an anti-neuroinflammatory add-on therapy for patients with multiple sclerosis (MS). The project, titled "ORAL N-ACETYLGLUCOSAMINE AS ANTI-NEUROINFLAMMATORY ADD-ON THERAPY FOR MULTIPLE SCLEROSIS (NANA-MS)", will be conducted by the University of...
- This $614,009 federal Project Grant award was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research into the molecular mechanisms of oligodendrocyte myelination and remyelination, which are critical processes for addressing demyelinating diseases of the central nervous system like multiple sclerosis. The awardee, Children's Hospital...
- This Project Grant award, totaling $547,846 and provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to optimize and characterize small molecule GPR17 antagonists for potential treatment of multiple sclerosis (MS). The research will focus on understanding the role of the GPR17 receptor in oligodendrocyte maturation and remyelination, with the goal of...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will fund the development of an in vitro platform to investigate the role of matrix metalloproteinase-9 (MMP-9) in blood-brain barrier permeability and neurovascular unit dysfunction in multiple sclerosis (MS). The $534,964 award to Michigan State University aims to enhance understanding of...