Project Grant R01NS140071
- This $4.5 million project grant from the National Institute on Aging, part of the Department of Health and Human Services, supports research under the Aging Research program (CFDA 93.866). The University of Michigan will examine racial inequities in neurological conditions like vascular contributions to cognitive impairment and dementia (VCID) and stroke. Leveraging the Reasons for Geographic and Racial Differences in Stroke study cohort of over 30,000 adults, the research aims to determine...
- This Project Grant award of $2,549,080.00, provided by the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), supports research to investigate the impact of SARS-CoV-2 infection on the cerebrovasculature as a risk factor for vascular contributions to cognitive impairment and dementia (VCID). The award, with a performance period from August 11, 2025 to July 31, 2029, will fund the University of Illinois to: Determine how prior SARS-CoV-2 infection influences...
- This Project Grant award of $2,403,545 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders federal grant program (CFDA 93.853), supports research to examine the epigenetic mechanisms linking social determinants of health (SDOH) exposures to vascular cognitive impairment and dementia (VCID) after intracerebral hemorrhage (ICH) stroke. The research, titled REACH-EPIVCID, will identify...
- This $1,120,805 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders federal grant program (CFDA 93.853), will support research to investigate how prior SARS-CoV-2 infection may increase the risk of vascular contributions to cognitive impairment and dementia (VCID). The research aims to: Determine how prior SARS-CoV-2 infection influences blood-brain barrier...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $431,750 to support a collaborative research project between Henry Ford Health and Michigan State University Health Sciences. The project aims to overexpress the CYP2C11 enzyme in peri-lesion astrocytes using an adeno-associated virus (AAV) vector, in order to increase cerebral...
- This federal Project Grant award, issued by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $4,693,249 to the University of California, Los Angeles (UCLA) to conduct research on defining the molecular spectrum of white matter vascular lesions that drive vascular cognitive impairment and dementia (VCID). The project aims to develop a better understanding of...
- The National Institute on Aging (NIA) has awarded a $640,906 project grant under CFDA 93.866 Aging Research to the University of Wisconsin-Madison to conduct research on "Elucidating Cerebrovascular Disease Pathways to Cognitive Decline with Vascular Neuroimaging." The 5-year project aims to utilize advanced neuroimaging techniques to understand the vascular contributions to cognitive impairment and dementia (VCID), and assess their relationship to Alzheimer's disease proteinopathy....
- This federal Project Grant award of $2,353,206.00, issued by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the role of the SPAK-NKCC1 protein complex in the choroid plexus and its contribution to blood-CSF barrier dysfunction in vascular contributions to cognitive impairment and dementia (VCID). The research aims to fill the...
- This Project Grant award for $2,398,590.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research to investigate the role of brain microcirculation and capillary endothelial cell energetics in the development of vascular cognitive impairment and dementia (VCID) observed in Alzheimer's disease (AD) and AD-related dementias. The...
- The U.S. National Institute of Neurological Disorders and Stroke (NINDS) awarded a $125,685 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Leland Stanford Junior University (Stanford University). The funding will support the development of an injectable hydrogel with an integrated urokinase plasminogen activator (uPA) motif and plasmid DNA (pDNA) platelet-derived growth factor B (PDGFB)-lipoplexes to be loaded into the...
This federal Project Grant award of $633,146 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to determine modifiable factors that impact post-stroke vascular cognitive impairment and dementia (VCID). The primary objectives are to: 1) quantify the association between performance of cognitively stimulating activities after stroke and post-stroke cognitive decline and VCID incidence, and 2) examine the contribution of sleep disorders like obstructive sleep apnea to post-stroke VCID. This 5-year award to the Regents of the University of Michigan aims to provide critical insights into practical interventions to prevent VCID, a highly disabling condition affecting up to one-third of stroke survivors for which no treatments currently exist.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $633.1k | 8/1/25 |